Results 101 to 110 of about 245,191 (321)

The use of TLR2 modified BMSCs for enhanced bone regeneration in the inflammatory micro-environment

Artificial Cells, Nanomedicine, and Biotechnology, 2019
The repair of periodontal bone tissue defects in patients with periodontitis is one of the major challenges for dentists. Stem cell-based bone regeneration has been considered as a promising strategy to restore the lost periodontal bone tissue.
Qin Zhou, Xiaoyu Gu, Jiachen Dong, Chao Zhu, Zhen Cai, Dongmei He, Chi Yang, Ling Xu, Jiawei Zheng   +8 more
doaj   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Concise Review: Periodontal Tissue Regeneration Using Stem Cells: Strategies and Translational Considerations

Stem Cells Translational Medicine, 2018
Periodontitis is a widespread disease characterized by inflammation‐induced progressive damage to the tooth‐supporting structures until tooth loss occurs.
Xin-Yue Xu, Xuan Li, Jia Wang, Xiao-Tao He, Hai-hua Sun, Faming Chen   +5 more
semanticscholar   +1 more source

Diffeomorphometric analysis of periodontal tissue regeneration [PDF]

, 2021
This project evaluated several image analysis methods on the irregular morphology of bone defect models in periodontal tissues. The study advanced image improvement technology for visualization of mineralized tissue regeneration. The current work will allow scientists to circumvent the current known limitations in evaluating trabeculae ...
openaire   +2 more sources

Membrane Guided Regeneration in Periodontal Tissues [PDF]

Journal of Membrane and Separation Technology, 2013
Periodontal regeneration is the restoration of lost periodontium or supporting tissues and includes the formation of new alveolar bone, new cementum and new periodontal ligament. The concept of GTR is based on the exclusion of gingival connective tissue cells and prevention of epithelial down growth into the wound, thereby allowing cells with ...
Jaisika Rajpal, Aakash Arora, Ruchika Prasad, Madhav Mukund Gupta   +3 more
openaire   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Maintained Properties of Aged Dental Pulp Stem Cells for Superior Periodontal Tissue Regeneration

Aging and Disease, 2019
Owing to excellent therapeutic potential, mesenchymal stem cells (MSCs) are gaining increasing popularity with researchers worldwide for applications in tissue engineering, and in treatment of inflammation-related and age-related disorders.
Linsha Ma, Jingchao Hu, Yu Cao, Yilin Xie, Hua Wang, Z. Fan, Chunmei Zhang, Jinsong Wang, Chu-Tse Wu, Songlin Wang   +9 more
semanticscholar   +1 more source

Biomaterial Scaffolds for Periodontal Tissue Engineering

Journal of Functional Biomaterials
Advanced periodontitis poses a significant threat to oral health, causing extensive damage and loss of both hard and soft periodontal tissues. While traditional therapies such as scaling and root planing can effectively halt the disease’s progression ...
Huanhuan Chen, Guangying Song, Tianmin Xu, Chenda Meng, Yunfan Zhang, Tianyi Xin, Tingting Yu, Yifan Lin, Bing Han   +8 more
doaj   +1 more source

Gene therapy with growth factors for periodontal tissue engineering : a review [PDF]

, 2011
The treatment of oral and periodontal diseases and associated anomalies accounts for a significant proportion of the healthcare burden, with the manifestations of these conditions being functionally and psychologically debilitating.
Gupta, Shipra, Mahendra, Aneet, Sood, Shaveta   +2 more
core   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source