Sixty years after the introduction of dental implants, it is clear that soft‐tissue integration is as essential as osseointegration. This review outlines how peri‐implant soft tissues develop, protect, and sometimes fail, revealing key knowledge gaps and new opportunities to improve long‐term implant stability.
Fabiana Aellos +6 more
wiley +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Knowledge, attitudes, and practices regarding periodontal assessment and co-management during orthodontic care among Moroccan dentists: a nationwide cross-sectional survey. [PDF]
Hbibi A +8 more
europepmc +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
DataSheet1_Prohibitin modulates periodontium differentiation in mice development.docx
Introduction: Prohibitin (PHB) is an essential scaffold protein that modulates signaling pathways controlling cell survival, metabolism, inflammation, and bone formation.
Jo-Young Suh (3535199) +15 more
core +1 more source
Prevalence and Determinants of Fluorosis and Association with Periodontal Health in an Endemic Region in Central India: A Community based Cross-sectional Study. [PDF]
Marskoley D, Sengupta T, Basu S.
europepmc +1 more source
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Chemerin Promotes Obesity-Accelerated Orthodontic Tooth Movement by Activating IRE1α-Dependent ER Stress in PDL Fibroblasts. [PDF]
Zhang D +7 more
europepmc +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
A Biomimetic Microfluidic Triple-compartment Periodontium-on-chip for Investigation of Inflammatory Responses in Periodontitis. [PDF]
R A +6 more
europepmc +1 more source

