Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Stem-cell regulation in periodontium formation and regeneration. [PDF]
Nagata M, Nagaoka C, Iwata T.
europepmc +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
The Role of Wnt Signaling in Age-Related Alveolar Bone Loss and Regeneration. [PDF]
Sung HH +12 more
europepmc +1 more source
Viruses, Periodontitis, and Systemic Diseases
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
Evaluation of salivary immunoglobulin A level in thalassemic patients with periodontitis in comparison with thalassemic patients with healthy periodontium [PDF]
BACKGROUND AND AIM: This study was conducted to evaluate salivary immunoglobulin A (IgA) level in thalassemic patients with periodontitis in comparison to thalassemic patients with healthy periodontium.
Arbabi, Parvin +3 more
core
Three-dimensional finite element analysis of bracketless clear aligner expansion with different buccal bone plate thicknesses. [PDF]
Yu T +9 more
europepmc +1 more source
Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling
Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon +4 more
wiley +1 more source
The association of multiple sclerosis with systemic inflammatory biomarkers: A case-control study exploring links with periodontal disease. [PDF]
Abed OK, Abbas RF.
europepmc +1 more source
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa +9 more
wiley +1 more source

