Results 111 to 120 of about 2,473,933 (318)

Sensitive and critical periods in visual sensory deprivation

open access: yesFrontiers in Psychology, 2013
While the demonstration of crossmodal plasticity is well established in congenital and early blind individuals, great debate still surrounds whether those who acquire blindness later in life can also benefit from such compensatory changes.
Patrice eVoss
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Swallowing activity assessed by ambulatory impedance-pH monitoring predicts awake and asleep periods at night. [PDF]

open access: yes, 2013
INTRODUCTION: Voluntary muscle activity, including swallowing, decreases during the night. The association between nocturnal awakenings and swallowing activity is under-researched with limited information on the frequency of swallows during awake and ...
Arevalo, F   +11 more
core   +1 more source

A Period Detector For Pseudo-Periodic Signals

open access: yes, 1998
Publication in the conference proceedings of EUSIPCO, Rhodes, Greece ...
openaire   +3 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Temporal relation between regression periods and transition periods

open access: yes, 2010
According to the literature about developmental changes, periods of instability and disorganization in the social and emotional behavior in both human and non-human primate, infancy precedes major developmental achievements or transitions (Heimann, 2003;
Plooij, Frans X.   +2 more
core   +1 more source

Evaluation of Metallothionein protein as a biomarker of Mercury pollution in Scat (Scatophagus argus)

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2010
Total Metallothionein (MT) biosynthesis and Mercury bioaccumulation under control & acute Mercury exposure were investigated in Scat (Scatophagus argus).
M. Sinaei; K. Darvish bastami; A. Ziadlo; S. Kordjazi; M. Vojdanian
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Addressing Menstrual Stigma: A Scoping Review on Menstrual Health Interventions in India

open access: yesSocial Sciences
(1) Background: Menstruation is subject to stigma worldwide, which has led to restrictive cultural norms and taboos rooted in religion, customs, and patriarchal systems.
Patricha Ottsen   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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