Results 201 to 210 of about 1,664,095 (269)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Obesogenic behaviors during structured periods among children and adolescents with intellectual and developmental disabilities: a systematic review and meta-analysis. [PDF]

Int J Behav Nutr Phys Act
Kiely KP, Brazendale K, Hill M, Burkart S, Beets MW, Adams EL, Armstrong B, St Laurent C, Hogan A, White Iii JW, Finnegan O, Culverhouse J, Holmes A, Weaver RG.   +13 more
europepmc   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Deceleration and rebound of hemagglutinin divergence in influenza B/Victoria across COVID-19 NPI phases (2016-2024). [PDF]

Front Microbiol
Zhang Y, Fu B, Yu C, Liu S, Wang Y, Wang Z, Wang K.   +6 more
europepmc   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Genomic characterization of invasive disease-causing <i>Streptococcus pneumoniae</i> in Lebanon, 2003-2025. [PDF]

Microb Genom
Dakroub F, King AC, Akl F, Zaghlout A, Hourani N, Hung H, Barada S, Boutros CF, Ferreira ADS, McGee L, Reslan L, Damaj S, Ghosn N, Matar GM, Araj GF, Abou Fayad A, Bentley SD, Lo SW, Dbaibo GS, For The Lebanese Inter-Hospital Pneumococcal Surveillance Program Investigators.   +19 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Clinical effects of two ozone therapy administration methods following mandibular third molar extraction: a parallel-group randomized clinical trial with exploratory salivary biomarker assessment. [PDF]

Clin Oral Investig
da Costa MG, Dallazen E, Pavelski MD, Delamura IF, Sampaio LV, Chaves-Neto AH, Faverani LP.   +6 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A study on the climate-driven spatiotemporal dynamics of influenza in Lanzhou spanning the COVID-19 era. [PDF]

Front Cell Infect Microbiol
Shi H, Zhang N, Wei H, Liang H, Zhang H, Zhang H, Wang B.   +6 more
europepmc   +1 more source