Results 11 to 20 of about 184,347 (251)

Renal resistive index is associated with acute kidney injury in COVID-19 patients treated in the intensive care unit

The Ultrasound Journal, 2021
Background Renal resistive index (RRI) is a promising tool for the assessment of acute kidney injury (AKI) in critically ill patients in general, but its role and association to AKI among patients with Coronavirus disease 2019 (COVID-19) is not known ...
Mårten Renberg, Olof Jonmarker, Naima Kilhamn, Claire Rimes-Stigare, Max Bell, Daniel Hertzberg   +5 more
doaj   +1 more source

Effects of pre-emptive pregabalin and multimodal anesthesia on postoperative opioid requirements in patients undergoing robot-assisted laparoscopic prostatectomy

BMC Urology, 2021
Background Previous findings indicate that pre-emptive pregabalin as part of multimodal anesthesia reduces opioid requirements compared to conventional anesthesia in patients undergoing robot-assisted laparoscopic prostatectomy (RALP).
K. Sisa, S. Huoponen, O. Ettala, H. Antila, T. I. Saari, P. Uusalo   +5 more
doaj   +1 more source

Nationwide case–control study of risk factors and outcomes for community-acquired sepsis

Scientific Reports, 2021
Sepsis is the main cause of death in the intensive care units (ICU) and increasing incidences of ICU admissions for sepsis are reported. Identification of patients at risk for sepsis and poor outcome is therefore of outmost importance.
Ann-Charlotte Lindström, Mikael Eriksson, Johan Mårtensson, Anders Oldner, Emma Larsson   +4 more
doaj   +1 more source

N -Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes

Journal of Neuroinflammation, 2022
Background The transient receptor potential vanilloid 1 (TRPV1) participates in thermosensation and inflammatory pain, but its immunomodulatory mechanisms remain enigmatic.
Jérémie Joffre, Erika Wong, Samira Lawton, Elliot Lloyd, Nina Nguyen, Fengyun Xu, Cristina Sempio, Lester Kobzik, Ivana Zlatanova, Mark Schumacher, Jost Klawitter, Hua Su, Katalin Rabl, Kevin Wilhelmsen, Che-Chung Yeh, Judith Hellman   +15 more
doaj   +1 more source

Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Perioperative Medicine, 2023
Background Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events.
A. Valadkhani, A. Gupta, M. Bell
doaj   +1 more source

Impact of gender on post- traumatic intensive care and outcomes

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Several reports indicate gender disparities in health care provision. There is a well-documented male patient dominance in intensive care unit (ICU) admittance.
Emma Larsson, Ann-Charlotte Lindström, Mikael Eriksson, Anders Oldner   +3 more
doaj   +1 more source

Lack of impact of nil-per-os (NPO) time on goal-directed fluid delivery in first case versus afternoon case starts: a retrospective cohort study

BMC Anesthesiology, 2019
Background Goal Directed Fluid Therapy (GDFT) represents an objective fluid replacement algorithm. The effect of provider variability remains a confounder.
R. Ryan Field, Tuan Mai, Samouel Hanna, Brian Harrington, Michael-David Calderon, Joseph Rinehart   +5 more
doaj   +1 more source

Neuronal metabolism role in ketogenic diet improvements in bortezomib-induced painful peripheral neuropathy mouse model

PAIN Reports
. Introduction:. A ketogenic diet (KD) can benefit a range of neurological conditions, including different types of peripheral neuropathy. Bortezomib (BTZ), a first-line chemotherapy for treating multiple myeloma, has neurotoxic effects and often induces
Lana L. Heslop, Trent K. Madden, Gentry Totta-Griese, Sarah J. Crowards, Will Hauser, Janelle Ryals, Kyle M. Baumbauer, Heather M. Wilkins, Douglas E. Wright   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Predictors of weaning failure in case of VA ECMO implantation

Scientific Reports, 2022
The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) for the treatment of refractory cardiogenic shock has increased significantly. Nevertheless, early weaning may be advisable to reduce the potential for severe complications.
Axelle Cusanno, Nadia Aissaoui, Vincent Minville, Jean Porterie, Caroline Biendel, Kim Volle, Laure Crognier, Jean-Marie Conil, Clément Delmas   +8 more
doaj   +1 more source