Results 31 to 40 of about 13,815 (244)

Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Perioperative Medicine, 2023
Background Elevated cardiac biomarkers, such as high-sensitivity cardiac Troponin T and N-terminal pro-B-type natriuretic peptide improve the prediction of major adverse cardiac events.
A. Valadkhani, A. Gupta, M. Bell
doaj   +1 more source

Impact of gender on post- traumatic intensive care and outcomes

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Several reports indicate gender disparities in health care provision. There is a well-documented male patient dominance in intensive care unit (ICU) admittance.
Emma Larsson, Ann-Charlotte Lindström, Mikael Eriksson, Anders Oldner   +3 more
doaj   +1 more source

Lack of impact of nil-per-os (NPO) time on goal-directed fluid delivery in first case versus afternoon case starts: a retrospective cohort study

BMC Anesthesiology, 2019
Background Goal Directed Fluid Therapy (GDFT) represents an objective fluid replacement algorithm. The effect of provider variability remains a confounder.
R. Ryan Field, Tuan Mai, Samouel Hanna, Brian Harrington, Michael-David Calderon, Joseph Rinehart   +5 more
doaj   +1 more source

Improving perioperative care [PDF]

, 2021
The concept of perioperative medicine has shifted the focus to what an anesthesiologist can do to improve not only intraoperative management but also the overarching surgical process and its outcome.
Mazzinari, G.
core   +1 more source

Screening for Mild Cognitive Impairment in the Preoperative Setting: A Narrative Review

, 2022
Cognitive impairment predisposes patients to the development of delirium and postoperative cognitive dysfunction. In particular, in older patients, the adverse sequelae of cognitive decline in the perioperative period may contribute to adverse outcomes ...
Buise, Marc, Roy Kessels, Bouwman, Arthur, Mariska te Pas, Arthur Bouwman, Kessels, Roy, Marcel Olde Rikkert, te Pas, Mariska, Marc Buise, Olde Rikkert, Marcel   +9 more
core   +1 more source

Neuronal metabolism role in ketogenic diet improvements in bortezomib-induced painful peripheral neuropathy mouse model

PAIN Reports
. Introduction:. A ketogenic diet (KD) can benefit a range of neurological conditions, including different types of peripheral neuropathy. Bortezomib (BTZ), a first-line chemotherapy for treating multiple myeloma, has neurotoxic effects and often induces
Lana L. Heslop, Trent K. Madden, Gentry Totta-Griese, Sarah J. Crowards, Will Hauser, Janelle Ryals, Kyle M. Baumbauer, Heather M. Wilkins, Douglas E. Wright   +8 more
doaj   +1 more source

Predictors of weaning failure in case of VA ECMO implantation

Scientific Reports, 2022
The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) for the treatment of refractory cardiogenic shock has increased significantly. Nevertheless, early weaning may be advisable to reduce the potential for severe complications.
Axelle Cusanno, Nadia Aissaoui, Vincent Minville, Jean Porterie, Caroline Biendel, Kim Volle, Laure Crognier, Jean-Marie Conil, Clément Delmas   +8 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Longitudinal Analysis of Traditional Inflammatory Markers (IL-6, CRP) Juxtaposed With Heparin-Binding Protein (HBP) and Serum Amyloid A Protein Component (SAA) During Acute Infection and Convalescence From COVID-19 Infection in the Context of Initial Viral Load and Markers of Tissue Destruction

Journal of Immunology Research
Conclusions: The persistence of inflammatory markers suggests ongoing inflammatory responses post-COVID-19 infection. Significant heterogeneity observed in inflammatory responses upon admission indicates multiple distinct inflammatory phenotypes, which ...
Ahmed Sayed Ahmed, Mohamed A. Mahmoud, Hossam Gad, Mohamed Antar, Abdelhamed Elgazar, Vasishta Anil, Daniel A. Diedrich, Krzysztof Laudanski   +7 more
doaj   +1 more source