Results 51 to 60 of about 275,167 (299)

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Albumin mass balance and kinetics in liver transplantation

Critical Care, 2018
Background In major abdominal surgery albumin is shifted from the circulation, presumably leaking into the interstitial space, contributing to a 30–40% decrease in plasma albumin concentration.
Mariam Amouzandeh, Greg Nowak, Anna Januszkiewicz, Jan Wernerman, Olav Rooyackers, Åke Norberg   +5 more
doaj   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

Perioperative Care

, 2020
The chapter covers pre-op assessment in the context of limited availability to tests and investigations outlining the key considerations that should be made in assessing fitness for and appropriateness of surgery. Key aspects of consent within different cultural contexts are explored as well as important consent considerations for quality improvement ...
Tom Bashford, Wayne Morriss, Clare Roques, Naomi Shamambo, Matt Wilkes   +4 more
openaire   +2 more sources

Prosthetic Mitral Valve Endocarditis due to Vagococcus fluvialis: A Case Report

Case Reports in Medicine
Infective endocarditis (IE) is an uncommon but life-threatening disease, most frequently caused by Staphylococcus aureus, streptococci, and enterococci. Vagococcus fluvialis is a Gram-stain positive coccus, phenotypically close to enterococci, and rarely
Camille Le Guillou, Yvon Ruch, Florian Baquer, Pierre Boyer, Michel Kindo, Mircea Cristinar, Sebastien Brua, Paul Michel Mertes, Walid Oulehri   +8 more
doaj   +1 more source

Randomized comparison of popliteal-sciatic perineural catheter tip migration and dislocation in a cadaver model using two catheter designs [PDF]

Korean Journal of Anesthesiology, 2017
BackgroundNew catheter-over-needle (CON) technology for continuous peripheral nerve blockade has emerged, but its effect on the risk of perineural catheter tip dislocation is unknown.
Lauren Steffel, Steven K. Howard, Lindsay Borg, Edward R. Mariano, Jody C. Leng, T. Edward Kim   +5 more
doaj   +1 more source

BEV-IP : perioperative chemotherapy with bevacizumab in patients undergoing cytoreduction and intraperitoneal chemoperfusion for colorectal carcinomatosis [PDF]

, 2015
Background: Selected patients with peritoneal carcinomatosis (PC) from colorectal cancer (CRC) benefit from cytoreductive surgery (CRS) combined with intraperitoneal chemoperfusion (IPC).
Ceelen, Wim, Liberale, Gabriel, Van Der Speeten, Kurt, Willaert, Wouter   +3 more
core   +2 more sources

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy

BMC Anesthesiology, 2018
Background Enhanced Recovery After Surgery (ERAS) pathways have been shown in multiple surgical disciplines to improve outcomes, including reduced opioid consumption, length of stay, and post-operative nausea and vomiting (PONV).
Catherine Chiu, Pedram Aleshi, Laura J. Esserman, Christina Inglis-Arkell, Edward Yap, Elizabeth L. Whitlock, Monica W. Harbell   +6 more
doaj   +1 more source

Relation between preoperative benzodiazepines and opioids on outcomes after total joint arthroplasty

Scientific Reports, 2021
To examine the association of preoperative opioids and/or benzodiazepines on postoperative outcomes in total knee and hip arthroplasty, we retrospectively compared postoperative outcomes in those prescribed preoperative opioids and/or benzodiazepines ...
Lisa V. Doan, Kristoffer Padjen, Deborah Ok, Adam Gover, Jawad Rashid, Bijan Osmani, Shirley Avraham, Jing Wang, Samir Kendale   +8 more
doaj   +1 more source