Levels of mannose-binding lectin (MBL) associates with sepsis-related in-hospital mortality in women
Background Mannose-binding lectin (MBL) mediates the innate immune response either through direct opsonisation of microorganisms or through activation of the complement system.
Sofie Jacobson+5 more
doaj +1 more source
AMPAkines potentiate the corticostriatal pathway to reduce acute and chronic pain
The corticostriatal circuit plays an important role in the regulation of reward- and aversion-types of behaviors. Specifically, the projection from the prelimbic cortex (PL) to the nucleus accumbens (NAc) has been shown to regulate sensory and affective ...
Fei Zeng+6 more
doaj +1 more source
Antidepressant drug use after intensive care: a nationwide cohort study
Modern intensive care has improved survival rates, but emerging evidence suggests a high prevalence of post-intensive care unit (ICU) health problems, including post-traumatic stress disorder, depression and anxiety. These symptoms may have a detrimental
Erik von Oelreich+4 more
doaj +1 more source
Erector spinae plane block for postoperative analgesia for above-the-knee amputation: a case report
Background Above-the-knee amputations (AKA) are common surgeries that frequently use neuraxial or peripheral nerve blocking techniques for both intraoperative and postoperative analgesia. It is not uncommon that patients present with contraindications to
Erica M. Langnas+2 more
doaj +1 more source
Improved Predictive Models for Acute Kidney Injury with IDEAs: Intraoperative Data Embedded Analytics [PDF]
Acute kidney injury (AKI) is a common and serious complication after a surgery which is associated with morbidity and mortality. The majority of existing perioperative AKI risk score prediction models are limited in their generalizability and do not fully utilize the physiological intraoperative time-series data.
arxiv +1 more source
Automatic Liver Segmentation from CT Images Using Deep Learning Algorithms: A Comparative Study [PDF]
Medical imaging has been employed to support medical diagnosis and treatment. It may also provide crucial information to surgeons to facilitate optimal surgical preplanning and perioperative management. Essentially, semi-automatic organ and tumor segmentation has been studied by many researchers.
arxiv
Background A plasma glutamine concentration outside the normal range at Intensive Care Unit (ICU) admission has been reported to be associated with an increased mortality rate. Whereas hypoglutaminemia has been frequently reported, the number of patients
Marie Smedberg+5 more
doaj +1 more source
Measurement of Individual Alteration in Perioperative ECGs During Elective Percutaneous Coronary Intervention [PDF]
The increasing availability of wearable electrocardiography (ECG) devices enables the continuous monitoring of individual ECG alterations. This could be beneficial for patients suffering from acute ischemia but with non-standard ECG findings that do not fit to the subject-independent and absolute thresholds defined in clinical guidelines. In this work,
arxiv
Abstract Objectives The objective of this study is to present our initial experience with a novel parenchymal clamp (NPC) developed to allow partial nephrectomies (PN) to be performed without whole kidney ischaemia. We compare patients who underwent PN with the NPC with those undergoing standard PNs. Methods The NPC applies pressure only to the portion
James Macneil+3 more
wiley +1 more source
Postoperative brain volumes are associated with one-year neurodevelopmental outcome in children with severe congenital heart disease [PDF]
Children with congenital heart disease (CHD) remain at risk for neurodevelopmental impairment despite improved peri- and intraoperative care. Our prospective cohort study aimed to determine the relationship between perioperative brain volumes and neurodevelopmental outcome in neonates with severe CHD. Pre- and postoperative cerebral MRI was acquired in
arxiv