Results 41 to 50 of about 68,826 (346)

Spatial Distribution of Macrophages During Callus Formation and Maturation Reveals Close Crosstalk Between Macrophages and Newly Forming Vessels [PDF]

, 2019
Macrophages are essential players in the process of fracture healing, acting by remodeling of the extracellular matrix and enabling vascularization. Whilst activated macrophages of M1-like phenotype are present in the initial pro-inflammatory phase of ...
Aulich, Linus, Buttgereit, Frank, Duda, Georg N., Fiedler, Alexander F., Gaber, Timo, Hauser, Anja E., Köhler, Markus, Lang, Annemarie, Niesner, Raluca A., Rauch, Ariana, Schmidt-Bleek, Katharina, Stefanowski, Jonathan   +11 more
core   +1 more source

Heterogeneity of murine periosteum progenitors involved in fracture healing

eLife, 2021
The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture healing.
Brya G Matthews, Sanja Novak, Francesca V Sbrana, Jessica L Funnell, Ye Cao, Emma J Buckels, Danka Grcevic, Ivo Kalajzic   +7 more
doaj   +1 more source

Predicting cortical bone adaptation to axial loading in the mouse tibia [PDF]

, 2015
The development of predictive mathematical models can contribute to a deeper understanding of the specific stages of bone mechanobiology and the process by which bone adapts to mechanical forces.
A. A. Pitsillides, A. F. Pereira, B. Javaheri, Cavanagh PR, Cowin SC, Frost HM, Phillips ATM, Robling AG, S. J. Shefelbine, Steck R   +9 more
core   +3 more sources

Periosteal stem cells: Research progress and application prospect

Kouqiang hemian waike zazhi
The periosteum, a connective tissue layer covering bone surfaces, possesses excellent bone regeneration capabilities and serves as the primary reservoir of stem cells for bone repair.
YI Zumu, DENG Chen, MAN Yi
doaj   +1 more source

Periosteum: A Highly Underrated Tool in Dentistry

International Journal of Dentistry, 2012
The ultimate goal of any dental treatment is the regeneration of lost tissues and alveolar bone. Under the appropriate culture conditions, periosteal cells secrete extracellular matrix and form a membranous structure.
Ajay Mahajan
doaj   +1 more source

The Bone-Forming Properties of Periosteum-Derived Cells Differ Between Harvest Sites

Frontiers in Cell and Developmental Biology, 2020
The development of alternatives for autologous bone grafts is a major focus of bone tissue engineering. To produce living bone-forming implants, skeletal stem and progenitor cells (SSPCs) are envisioned as key ingredients.
Lisanne C. Groeneveldt, Lisanne C. Groeneveldt, Lisanne C. Groeneveldt, Lisanne C. Groeneveldt, Lisanne C. Groeneveldt, Tim Herpelinck, Tim Herpelinck, Marina Maréchal, Marina Maréchal, Constantinus Politis, Constantinus Politis, Wilfred F. J. van IJcken, Wilfred F. J. van IJcken, Danny Huylebroeck, Danny Huylebroeck, Liesbet Geris, Liesbet Geris, Liesbet Geris, Liesbet Geris, Eskeatnaf Mulugeta, Frank P. Luyten, Frank P. Luyten, Frank P. Luyten   +22 more
doaj   +1 more source

A periosteum-derived cell line to study the role of BMP/TGFβ signaling in periosteal cell behavior and function

Frontiers in Physiology, 2023
The periosteum is a thin tissue surrounding each skeletal element that contains stem and progenitor cells involved in bone development, postnatal appositional bone growth, load-induced bone formation, and fracture repair.
Emily R. Moore, David E. Maridas, Laura Gamer, Gavin Chen, Kathryn Burton, Vicki Rosen   +5 more
doaj   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Periosteum: biology, regulation, and response to osteoporosis therapies [PDF]

, 2004
Periosteum contains osteogenic cells that regulate the outer shape of bone and work in coordination with inner cortical endosteum to regulate cortical thickness and the size and position of a bone in space.
Allen, Matthew R., Burr, David B., Hock, Janet M.   +2 more
core   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source