Results 51 to 60 of about 2,384,085 (319)

Disseminated Intracranial and Spinal Neurenteric Cysts: A Case Report and Literature Review

open access: yesCase Reports in Neurological Medicine
Neurenteric cysts (NECs) are rare congenital, benign lesions of the central nervous system (CNS), predominantly located within the spinal cord. However, they may also occur less frequently within the brainstem, fourth ventricle, or cerebellopontine angle
Jan Kuschick Feher   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation

open access: yesFrontiers in Neuroscience, 2017
Methylglyoxal (MG) is a metabolite of glucose that may contribute to peripheral neuropathy and pain in diabetic patients. MG increases intracellular calcium in sensory neurons and produces behavioral nociception via the cation channel transient receptor ...
Ryan B. Griggs   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Classical supravalvar aortic stenosis and peripheral pulmonary stenosis [PDF]

open access: yes, 2014
Supravalvar aortic stenosis as well as peripheral pulmonary stenosis are rare forms of congenital heart disease, which occur, however, relatively frequently in association.
Ramakrishnan, S.   +3 more
core  

Left peripheral arguments and discourse interface strategies in Yucatec Maya

open access: yes, 2012
Skopeteas S, Verhoeven E. Left peripheral arguments and discourse interface strategies in Yucatec Maya. In: Neeleman A, Kucerova I, eds. Contrasts and positions in information structure.
Verhoeven, Elisabeth   +5 more
core   +1 more source

Ameloblastoma: A clinicoradiographic and histopathologic correlation of 11 cases seen in Goa during 2008-2012

open access: yesContemporary Clinical Dentistry, 2014
Objectives: The purpose of this case series was to compare the clinical, radiographic, and histopathologic features of 11 cases of ameloblastoma that reported to the Goa Dental College and Hospital over a period of 4 years from January 2008 to December ...
Nigel R Figueiredo   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Peripheral cytokine responses to Trichuris muris reflect those occurring locally at the site of infection [PDF]

open access: yes, 2000
The study of human cellular immune responses to parasite infection under field conditions is very complex. Often, the only practical site from which to sample the cellular responses is the peripheral blood.
Betts, Catherine   +8 more
core   +1 more source

Association between oxidative balance scores and peripheral artery disease in US adults: a cross-sectional study

open access: yesFrontiers in Nutrition
BackgroundThe Oxidative Balance Score (OBS) quantifies the overall oxidative stress burden, with higher scores indicating greater antioxidant (relative to prooxidant) activity.
Min Zhou   +9 more
doaj   +1 more source

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