Results 71 to 80 of about 2,384,085 (319)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Peripheral neuropathies of childhood
Includes synopsis.Incldues bibliographical references (p. 195-220).Peripheral nerve disease was described by Galen (AD 130-200) over a thousand years ago.(3) Detailed anatomical illustrations were documented by Andreas Vesalius in his major work 'De ...
Wilmshurst, Jo
core
Background The optimal treatment of complicated type B aortic dissection (cTBAD) involving arch anomalies remain unclear. Methods We consecutively enrolled patients with cTBAD involving arch anomalies who underwent endovascular repair using a single ...
Mengyang Kang +5 more
doaj +1 more source
Management of a rare case of peripheral squamous odontogenic tumor of the gingiva
Odontogenic tumors (OTs) arising from the periodontium are quite rare. Squamous OT (SOT) is one such neoplasm which has an exceedingly rare occurrence.
Ramamurti Anjana +3 more
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Current insights into drug-coated balloons for peripheral arterial disease
Introduction: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. It is often associated with coronary and/or cerebral vascular involvement, leading to a higher risk of cardiovascular and cerebrovascular events, among which ...
Virga V +7 more
core +1 more source
Foot arteriovenous malformation: A single-institutional Experience
Background: Arterio venous malformations (AVM) encompass a wide spectrum of lesions that can present as an incidental finding or produce potentially life- or limb threatening complications.
Dheepak Selvaraj +11 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
LRP-1 Regulates Schwann Cell Motility by its Effects of the GTPases, Rac1 and Rho
Low-density lipoprotein receptor-related protein (LRP-1) functions in endocytosis and in cell signaling directly (binding signaling adapter proteins) or indirectly (by regulating levels of other cell signaling receptors). In the peripheral nervous system
Jo M +3 more
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