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Mycolactone Diffuses into the Peripheral Blood of Buruli Ulcer Patients - Implications for Diagnosis and Disease Monitoring. [PDF]
BACKGROUND: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis ...
Le Chevalier, Fabien +53 more
core +2 more sources
Many observational studies and experiments have found a strong association between lipid levels and adipokines and multiple myeloma (MM), but the causal relationship between lipid levels, adipokines and MM remains to be determined.
Yi Ding +4 more
doaj +1 more source
Ahmed Badar,1 Ayad Mohammed Salem,1 Abdullah Omar Bamosa,1 Hatem Othman Qutub,2 Rakesh Kumar Gupta,2 Intisar Ahmad Siddiqui3 1Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Department of ...
Badar A +5 more
doaj
Objectives To investigate peripheral cytopenia in patients with splenomegaly due to hepatitis B-related cirrhotic portal hypertension (HBRCPH) by comparing blood cell counts from enlarged spleens with peripheral blood.
Xiaoyu Han +7 more
doaj +1 more source
The cellular communication electromagnetic fields have become a significant physical environmental factor recently, which cannot but cause reasonable concern due to the possible adverse effects of human health.
Valentina S. Orlova +3 more
doaj +1 more source
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
The nature of the dependence of the intensity of free radical processes in the peripheral blood of donors on the dose of radiation in vitro (0.5 - 3.0 Gy) related to the parameters of the prooxidant-antioxidant ratio (PAR) and the content of malonic ...
L. I. Makovetska +3 more
doaj +1 more source
Colorectal cancer (CRC) is a major cause of cancer mortality and morbidity. Despite advances in chemotherapy and targeted therapy, unsustainable clinical benefit was noted due to recurrence and therapy resistance.
Yi-Tung Chen +19 more
doaj +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

