Results 61 to 70 of about 3,965,736 (309)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Mathematical modeling of compensations of anemia by means of the appearing additional cell's flow into peripheral blood as a result of anemia

Бюллетень сибирской медицины, 2008
For evaluation of the efficiency estimation of compensation of anemia by means of the appearing additional cell’s flaw into peripheral blood the method of has been used.
V. V. Svischenko, N. A. Stakhin
doaj   +1 more source

Optimization of peripheral blood volume for in silico reconstitution of the human B‐cell receptor repertoire

FEBS Open Bio, 2022
B cells recognize antigens via membrane‐expressed B‐cell receptors (BCR) and antibodies. Similar human BCR sequences are frequently found at a significantly higher frequency than that theoretically calculated.
Hyunho Lee, Duck Kyun Yoo, Jerome Han, Ki Hyun Kim, Jinsung Noh, Yonghee Lee, Eunjae Lee, Sunghoon Kwon, Junho Chung   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

In vitro peripheral blood mononuclear cell proliferation in a crossbred cattle population [PDF]

, 2005
Immune function measured by Staphylococcus aureus- and phytohemagglutinin- (PHA-) induced cell proliferation was assessed in a population of 445 genetically defined, F2 and backcross Charolais-Holstein crossbred cattle when the animals were approximately
Williams, J., ONeill, R.G., Young, F.J., Fitzpatrick, J.L., Williams, J.L., Woolliams, J.A., O'Neill, R.G., Glass, Elizabeth, Woolliams, John, Glass, E.J.   +9 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

ABO incompatibility haploidentical peripheral blood stem cell transplantation combined with a single cord blood unit for severe aplastic anemia patients

SAGE Open Medicine
Objective: To observe the efficacy of haploidentcial peripheral blood stem cell transplantation combined with a single unrelated cord blood unit for severe aplastic anemia patients with donor-recipient ABO incompatibility.
Xiaoning Wang, Yuqi Wang, Aiman Saulat, Ruimin Liu, Juan Ren, Huachao Zhu, Mei Zhang, Pengcheng He   +7 more
doaj   +1 more source

B-cell kinetics in humans: rapid turnover of peripheral blood memory cells.

, 2005
Information about the kinetic behavior and lifespan of lymphocytes is crucial to understanding the mechanisms that regulate processes such as immunologic memory. We have used in vivo labeling of dividing cells with 6,6-(2)H(2)-glucose, combined with cell
Wallace, Diana L, Macallan, DC, Griffin, GE, de Lara, C, George E. Griffin, Asquith, B, Derek C. Macallan, Panayiotakopoulos, George, de Lara, Catherine, Ghattas, Hala, Zhang, Yan, Peter C. L. Beverley, Griffin, George E, Panayiotakopoulos, G, Andrew Worth, George Panayiotakopoulos, Macallan, Derek C, Beverley, Peter, Worth, A, Beverley, Peter CL, Zhang, Y, Ghattas, H, Tough, David F, Diana L. Wallace, Hala Ghattas, Wallace, DL, Becca Asquith, Tough, DF, Worth, Andrew, David F. Tough, Asquith, Becca, Yan Zhang, Beverley, PC, Catherine de Lara   +33 more
core   +1 more source