Changes in peripheral blood mononuclear cell electrical properties in response to viral exposure and vaccination. [PDF]
Clarke KSP +6 more
europepmc +1 more source
Baseline Peripheral Blood Mononuclear Cell Transcriptomics Before Ustekinumab Treatment Is Linked With Crohn's Disease Clinical Response at 1 Year. [PDF]
Granot M +10 more
europepmc +1 more source
ChromNet enables accurate cross‐cell‐type prediction of chromatin architecture from DNA and epigenetic profiles alone, capturing both conserved and cell‐type‐specific (including disease‐associated) structural features. Its noise‐perturbed multi‐task learning design enhances generalization, enabling precise reconstruction of 3D genome organization even ...
Bin Wang +5 more
wiley +1 more source
Peripheral blood mononuclear cell DNA methylation biomarkers for prognostic stratification in Chinese lung adenocarcinoma: a genome-wide epigenetic profiling study. [PDF]
Li P +10 more
europepmc +1 more source
Altered expression of apoptosis-related genes in rheumatoid arthritis peripheral blood mononuclear cell and related miRNA regulation. [PDF]
Ebrahimian H +7 more
europepmc +1 more source
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang +12 more
wiley +1 more source
Immune Modulatory Effects of PD-1/PD-L1 in Myasthenia Gravis: Insights From Peripheral Blood Mononuclear Cell Analysis. [PDF]
Li J +11 more
europepmc +1 more source
Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome. [PDF]
Kumar R +12 more
europepmc +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source

