Results 11 to 20 of about 250,250 (265)

Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers

Genome Medicine, 2023
Background Systemic and local profiles have each been associated with asthma, but parsing causal relationships between system-wide and airway-specific processes can be challenging.
Lingdi Zhang, Yoojin Chun, Haritz Irizar, Zoe Arditi, Galina Grishina, Alexander Grishin, Alfin Vicencio, Supinda Bunyavanich   +7 more
doaj   +1 more source

Molecular Detection of Human Herpesvirus-8 in Plasma and Peripheral Blood Mononuclear Cells of Patients with Cryptogenic Cirrhosis [PDF]

Journal of Kerman University of Medical Sciences, 2022
Background: Human herpesvirus-8 is the infectious etiology of endothelial origin in tumours with blood disorders. However, in some cirrhotic patients, no etiology can be identified, and such cases are known as cryptogenic cirrhosis. The aim of this study
Farah Bokharaei-Salim, Mohammad Hossein Razizadeh, Maryam Esghaei, Fatemeh Haghparvar, Khashayar Hesamizadeh, Hossein Keyvani   +5 more
doaj   +1 more source

Increased CEACAM1 expression on peripheral blood neutrophils in patients with rheumatoid arthritis

Frontiers in Immunology, 2022
Altered expression of adhesion molecules in immune cells has been demonstrated in rheumatoid arthritis (RA). Carcinoembryonic–antigen–related cell–adhesion molecule 1 (CEACAM1) is an adhesion molecule that acts as a coinhibitory receptor in the immune ...
Haruki Matsumoto, Yuya Fujita, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Makiko Yashiro-Furuya, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Takeshi Machida, Hiroshi Watanabe, Kiyoshi Migita   +14 more
doaj   +1 more source

Transplantation of autologous peripheral blood mononuclear cells in the subarachnoid space for amyotrophic lateral sclerosis: a safety analysis of 14 patients

Neural Regeneration Research, 2017
There is a small amount of clinical data regarding the safety and feasibility of autologous peripheral blood mononuclear cell transplantation into the subarachnoid space for the treatment of amyotrophic lateral sclerosis.
Xiao-yan Li, Zhan-hua Liang, Chao Han, Wen-juan Wei, Chun-li Song, Li-na Zhou, Yang Liu, Ying Li, Xiao-fei Ji, Jing Liu   +9 more
doaj   +1 more source

Human Dendritic Cell Subset Isolation by Magnetic Bead Sorting: A Protocol to Efficiently Obtain Pure Populations

Bio-Protocol, 2023
Dendritic cells have been investigated for cell-based immunotherapy for various applications. The low abundance of dendritic cells in blood hampers their clinical application, resulting in the use of monocyte-derived dendritic cells as an alternative ...
Georgina Flórez-Grau, Jorge Cuenca Escalona, Helena Lacasta-Mambo, Daphne Roelofs, Johanna Bödder, Ruben Beuk, Gerty Schreibelt, I Jolanda de Vries   +7 more
doaj   +1 more source

Mitogen-stimulated cell proliferation and cytokine production in major depressive disorder patients

BMC Psychiatry, 2018
Background Major depressive disorder (MDD) is related to human’s immune status, and immunological indicators such as mitogen stimulated cell proliferation and cytokines may become candidate biomarkers for disease diagnosis.
Ping Lin, Bingyu Ding, Yunqiang Wu, Ke Dong, Qingtian Li   +4 more
doaj   +1 more source

Optimizing the method for generation of integration-free induced pluripotent stem cells from human peripheral blood

Stem Cell Research & Therapy, 2018
Background Generation of induced pluripotent stem cells (iPSCs) from human peripheral blood provides a convenient and low-invasive way to obtain patient-specific iPSCs.
Haihui Gu, Xia Huang, Jing Xu, Lili Song, Shuping Liu, Xiao-bing Zhang, Weiping Yuan, Yanxin Li   +7 more
doaj   +1 more source

A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells. [PDF]

PLoS ONE, 2009
Studies of the immunological environment in the female genital tract (FGT) are critical for the development of vaccines or microbicides to halt the spread of sexually transmitted infections.
Rachel E Horton, Nadine Kaefer, Elijah Songok, Fernando B Guijon, Nadia Kettaf, Geneviève Boucher, Rafick-Pierre Sekaly, T Blake Ball, Frank A Plummer   +8 more
doaj   +1 more source

Bovine-associated staphylococci and mammaliicocci trigger T-lymphocyte proliferative response and cytokine production differently

Journal of Dairy Science, 2023
: We examined whether distinct staphylococcal and mammaliicoccal species and strains trigger B- and T-lymphocyte proliferation and interleukin (IL)-17A and interferon (IFN)-γ production by peripheral blood mononuclear cells in nulliparous, primiparous ...
Fernando N. Souza, Kamila R. Santos, José A. Ferronatto, Eduardo M. Ramos Sanchez, Bruno Toledo-Silva, Marcos B. Heinemann, Sarne De Vliegher, Alice M.M.P. Della Libera   +7 more
doaj   +1 more source

Vasculogenically conditioned peripheral blood mononuclear cells inhibit mouse immune response to induced pluripotent stem cell-derived allogeneic cardiac grafts.

PLoS ONE, 2019
Allogeneic transplantation of induced pluripotent stem cell (iPSC)-derived cardiomyocytes is apromising treatment for cardiac diseases, although immune rejection by the recipient poses a concern. In this study, we aimed to investigate whether concomitant
Noriyuki Kashiyama, Shigeru Miyagawa, Satsuki Fukushima, Takuji Kawamura, Ai Kawamura, Shohei Yoshida, Yuki Nakamura, Akima Harada, Haruchika Masuda, Koichi Toda, Takayuki Asahara, Yoshiki Sawa   +11 more
doaj   +1 more source