Results 271 to 280 of about 412,823 (364)

Use of serum-free media for peripheral blood mononuclear cell culture and the impact on T and B cell readouts. [PDF]

Front Toxicol
Cochrane S, Saib O, Sheffield D.
europepmc   +1 more source

Patterns of Gene Expression in Peripheral Blood Mononuclear Cells and Outcomes from Patients with Sepsis Secondary to Community Acquired Pneumonia

, 2014
Patrícia Severino, Eliézer Silva, Giovana Lótici Baggio-Zappia, Milena Karina Coló Brunialti, Laura Alejandra Nucci, Otelo Rigato, Ismael Dale Cotrim Guerreiro da Silva, Flávia Ribeiro Machado, Reinaldo Salomão   +8 more
openalex   +2 more sources

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

Dual-release hydrocortisone treatment improves serum and peripheral blood mononuclear cell inflammatory and immune profiles in patients with autoimmune primary adrenal insufficiency. [PDF]

Front Immunol
Tomasello L, Coppola A, Pizzolanti G, Giordano C, Arnaldi G, Guarnotta V.   +5 more
europepmc   +1 more source

Prevailing vitamin D status influences mitochondrial and glycolytic bioenergetics in peripheral blood mononuclear cells obtained from adults

, 2016
Emily Calton, Kevin N. Keane, Mário J. Soares, Jordan Rowlands, Philip Newsholme   +4 more
openalex   +1 more source

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

Advanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li, Jiankai Dong, Zhengkun Liu, Chaoke Zhang, Jisen Li, Ying Tao, Ding Yang, Yansong Liu, Haoting Chen, Lu Liu, Jingsen Ji, Feng Cao, Dan Ding, Qian Liu, Chenxing Fu, Weisheng Guo   +15 more
wiley   +1 more source

Peripheral blood mononuclear cell respiratory function is associated with progressive glaucomatous vision loss. [PDF]

Nat Med
Petriti B, Rabiolo A, Chau KY, Williams PA, Montesano G, Lascaratos G, Garway-Heath DF.   +6 more
europepmc   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

A Means to an End(othelium): Using Peripheral Blood Mononuclear Cell 'Omics to Peer into the Pulmonary Vasculature. [PDF]

Ann Am Thorac Soc
Chiles JW.
europepmc   +1 more source

RNA from stabilized whole blood enables more comprehensive immune gene expression profiling compared to RNA from peripheral blood mononuclear cells

, 2020
Fleur van der Sijde, Yunlei Li, Rick Schraauwen, Willem de Koning, Casper H.J. van Eijck, Dana A. M. Mustafa   +5 more
openalex   +2 more sources