Results 21 to 30 of about 412,823 (364)

CD14+ cells from peripheral blood positively regulate hematopoietic stem and progenitor cell survival resulting in increased erythroid yield

Haematologica, 2015
Expansion of erythroblasts from human peripheral blood mononuclear cells is 4- to 15-fold more efficient than that of CD34+ cells purified from peripheral blood mononuclear cells.
Esther Heideveld, Francesca Masiello, Manuela Marra, Fatemehsadat Esteghamat, Nurcan Yağcı, Marieke von Lindern, Anna Rita F. Migliaccio, Emile van den Akker   +7 more
doaj   +1 more source

Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. [PDF]

, 2003
CXCR4 expression on feline peripheral blood mononuclear cells (PBMC) was analyzed. While monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans.
Cannon, C.A., Hosie, M.J., Willett, B.J.
core   +2 more sources

High-throughput chromatin accessibility profiling at single-cell resolution. [PDF]

, 2018
Here we develop a high-throughput single-cell ATAC-seq (assay for transposition of accessible chromatin) method to measure physical access to DNA in whole cells.
Bostick, Magnolia, Brower, Kara, Farmer, Andrew, Fordyce, Polly, Greenleaf, William, Klemm, Sandy, Linnarsson, Sten, Mann, Ishminder, Mezger, Anja, Mir, Alain   +9 more
core   +3 more sources

Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key drivers

Genome Medicine, 2023
Background Systemic and local profiles have each been associated with asthma, but parsing causal relationships between system-wide and airway-specific processes can be challenging.
Lingdi Zhang, Yoojin Chun, Haritz Irizar, Zoe Arditi, Galina Grishina, Alexander Grishin, Alfin Vicencio, Supinda Bunyavanich   +7 more
doaj   +1 more source

Molecular Detection of Human Herpesvirus-8 in Plasma and Peripheral Blood Mononuclear Cells of Patients with Cryptogenic Cirrhosis [PDF]

Journal of Kerman University of Medical Sciences, 2022
Background: Human herpesvirus-8 is the infectious etiology of endothelial origin in tumours with blood disorders. However, in some cirrhotic patients, no etiology can be identified, and such cases are known as cryptogenic cirrhosis. The aim of this study
Farah Bokharaei-Salim, Mohammad Hossein Razizadeh, Maryam Esghaei, Fatemeh Haghparvar, Khashayar Hesamizadeh, Hossein Keyvani   +5 more
doaj   +1 more source

Expression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance. [PDF]

, 2014
BACKGROUND: Colorectal cancer (CRC) progression is associated with suppression of host cell-mediated immunity and local immune escape mechanisms. Our aim was to assess the immune function in terms of expression of TNF, IFNG and FOXP3 in CRC. METHODS:
A D Beggs, A Merlo, AG Heriot, AM Wolf, C Evans, C Grunfeld, C Loddenkemper, CF Evans, D Kumar, DJ Needham, E Sato, F Balkwill, G Brandacher, G Galizia, G Pawelec, H Nakayama, IC Talbot, JC Harrison, JD Fontenot, JK Polansky, KE Sullivan, KJ Livak, KL Ling, L Xue, LA Liotta, LM Ebert, M Kanazawa, M Kim, M Morris, M Shibata, N Hiraoka, N Kobayashi, N Watanabe, P Quirke, P Radhakrishnan, P Salama, PJ Coffer, R Somasundaram, RJ O’Hara, S Hinz, S Hori, S K Ganapathi, S Ogino, S V Hodgson, SL Clarke, SM Phillips, T Blankenstein, T Sato, TJ Curiel, TJ Curiel, VC Petersen, W Zou, X Chen   +52 more
core   +2 more sources

Bioenergetic analysis of human peripheral blood mononuclear cells [PDF]

Clinical and Experimental Immunology, 2015
SummaryLeucocytes respond rapidly to pathogenic and other insults, with responses ranging from cytokine production to migration and phagocytosis. These are bioenergetically expensive, and increased glycolytic flux provides adenosine triphosphate (ATP) rapidly to support these essential functions. However, much of this work is from animal studies.
Jones, N., Piasecka, J., Bryant, A. H., Jones, R. H., Skibinski, D. O. F., Francis, Nigel J., Thornton, C. A.   +6 more
openaire   +4 more sources

Increased CEACAM1 expression on peripheral blood neutrophils in patients with rheumatoid arthritis

Frontiers in Immunology, 2022
Altered expression of adhesion molecules in immune cells has been demonstrated in rheumatoid arthritis (RA). Carcinoembryonic–antigen–related cell–adhesion molecule 1 (CEACAM1) is an adhesion molecule that acts as a coinhibitory receptor in the immune ...
Haruki Matsumoto, Yuya Fujita, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Makiko Yashiro-Furuya, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Takeshi Machida, Hiroshi Watanabe, Kiyoshi Migita   +14 more
doaj   +1 more source

Peripheral blood mononuclear cell secretome for tissue repair [PDF]

Apoptosis, 2016
For almost two decades, cell-based therapies have been tested in modern regenerative medicine to either replace or regenerate human cells, tissues, or organs and restore normal function. Secreted paracrine factors are increasingly accepted to exert beneficial biological effects that promote tissue regeneration.
Beer, Lucian, Mildner, Michael, Gyöngyösi, Mariann, Ankersmit, Hendrik Jan   +3 more
openaire   +2 more sources

Transplantation of autologous peripheral blood mononuclear cells in the subarachnoid space for amyotrophic lateral sclerosis: a safety analysis of 14 patients

Neural Regeneration Research, 2017
There is a small amount of clinical data regarding the safety and feasibility of autologous peripheral blood mononuclear cell transplantation into the subarachnoid space for the treatment of amyotrophic lateral sclerosis.
Xiao-yan Li, Zhan-hua Liang, Chao Han, Wen-juan Wei, Chun-li Song, Li-na Zhou, Yang Liu, Ying Li, Xiao-fei Ji, Jing Liu   +9 more
doaj   +1 more source