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Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures

Cannabis and Cannabinoid Research, 2022
Background: Cannabidiol (CBD), one major nonintoxicating phytocannabinoid from Cannabis sativa demonstrated anti-inflammatory effects in animal models of several inflammatory conditions, including arthritis. However, it is still unknown which cell types mediate these anti-inflammatory effects of CBD, and, since CBD binds to a plethora of receptors and ...
Torsten Lowin   +4 more
openaire   +2 more sources

Overview: Autologous Peripheral Blood Mononuclear Cells

Journal of Stem Cell Research and Transplantation, 2021
The implant of autologous mononuclear cells is an avant-garde method based on the use of a cell population within our body to regenerate tissues that have been damaged by various pathological events. The biological assumption is the richness and complexity of biochemical and cellular phenomena inherent in both organism response to damage and tissue ...
Petrungaro A, Scudo F, Quartarone E
openaire   +1 more source

Peripheral blood mononuclear cell activation sustains seizure activity

Epilepsia, 2021
AbstractObjectiveThe influx of immune cells and serum proteins from the periphery into the brain due to a dysfunctional blood‐brain barrier (BBB) has been proposed to contribute to the pathogenesis of seizures in various forms of epilepsy and encephalitis. We evaluated the pathophysiological impact of activated peripheral blood mononuclear cells (PBMCs)
Laura Librizzi   +7 more
openaire   +3 more sources

Hsp70 release from peripheral blood mononuclear cells

Biochemical and Biophysical Research Communications, 2004
There are an increasing number of studies reporting the presence of Hsps in human serum. We have investigated the release of Hsp70 into blood and culture medium from peripheral blood mononuclear cells (PBMCs), and whether this release is due to cell damage or active secretion from the cells.
Hunter-Lavin, Claire   +5 more
openaire   +3 more sources

Proteomic map of peripheral blood mononuclear cells

PROTEOMICS, 2008
AbstractIn the field of proteomics extensive efforts have been focused on the knowledge of proteins expressed by different cell types. In particular, enormous progress has been done in the characterization of blood cellular components. In this work, we have established a public 2‐DE database for human peripheral blood mononuclear cells (PBMCs) proteins.
VERGARA, DANIELE   +3 more
openaire   +2 more sources

Isolation and cryopreservation of peripheral blood mononuclear cells

2023
The study of peripheral blood mononuclear cells (PBMCs) in immune-mediated diseases, such as celiac disease (CD), is important to uncover pathogenesis, find new biomarkers and discover and evaluate new treatments. Many studies have been published about the use and value of PBMCs in CD such as those including enzyme-linked immunospot (ELISPOT) assays ...
Sara, Gómez-Aguililla   +3 more
openaire   +2 more sources

Hepatitis C Virus in Peripheral Blood Mononuclear Cells

American Journal of Clinical Pathology, 1992
RNA extracted from plasma and peripheral blood mononuclear cells of patients with chronic hepatitis C were used as the template for reverse transcription followed by double in vitro enzymatic amplification with nested primers. Hepatitis C virus was detected in 14 of 15 (93.3%) plasma specimens and in 8 of 15 (53.3%) peripheral blood mononuclear cell ...
T T, Hsieh   +4 more
openaire   +2 more sources

Isolation of Human Peripheral Blood Mononuclear Cells (PBMCs)

Current Protocols in Microbiology, 2007
AbstractIn this appendix, several basic methods are described for preparation of primary B lymphocyte. Curr. Protoc. Microbiol. 6:A.4C.1‐A.4C.9. © 2007 by John Wiley & Sons, Inc.
Lan, Ke   +4 more
openaire   +3 more sources

Opiates, Human Peripheral Blood Mononuclear Cells, and HIV

1991
Remarkably, interest in the pathogenetic effect of opiates on the course of bacterial infection can be traced to the late 19th century (1). Although the infectious disease complications of intravenous (IV) drug use were clearly recognized by the mid-20th century (2,3), serious attention to the mechanisms whereby opiates might participate in the ...
P K, Peterson   +4 more
openaire   +2 more sources

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