Results 51 to 60 of about 298,696 (311)

A gene signature for post-infectious chronic fatigue syndrome [PDF]

, 2009
Background: At present, there are no clinically reliable disease markers for chronic fatigue syndrome. DNA chip microarray technology provides a method for examining the differential expression of mRNA from a large number of genes.
Gow John W, Herzyk, Pawel, Gow, J.W., Celia Cannon, Behan Peter O, Hagan Suzanne, Suzanne Hagan, Behan, Peter O., Hagan, S., Herzyk, P., Chaudhuri, A., John W Gow, Gow, John W., Chaudhuri, Abhijit, Peter O Behan, Cannon Celia, Cannon, Celia, Behan, P.O., Abhijit Chaudhuri, Pawel Herzyk, Cannon, C., Hagan, Suzanne; id_orcid, Herzyk Pawel, Chaudhuri Abhijit   +23 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

PROLIFERATIVE AND SECRETORY RESPONSE OF MONONUCLEAR LEUCOCYTES TO COMBINED INFLUENCE OF ETHAMBUTOL AND MYCOBACTERIAL ANTIGENE

Медицинская иммунология, 2014
. The article deals with results of studying combined effects of ethambutol and protein antigen of Мycobacterium tuberculosis upon proliferative response and cytokine-producing ability of peripheral blood mononuclear cells in patients with infiltrative ...
V. A. Serebryakova, O. A. Vasil'eva, O. I. Urazova, V. V. Novitsky, O. V. Voronkova, A. K. Strelis, T. E. Budkina, R. R. Hasanova, I. O. Naslednikova   +8 more
doaj   +1 more source

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells [PDF]

, 2003
Background— Transplantation of ex vivo expanded circulating endothelial progenitor cells (EPCs) from peripheral blood mononuclear cells improves the neovascularization after critical ischemia. However, the origin of the endothelial progenitor lineage and
Dimmeler, S, Heeschen, C, Aicher, A, Urbich, C, Zeiher, AM, Dernbach, E   +5 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Dopamine Receptor Gene Expression Changes in Peripheral Blood Mononuclear Cells from Schizophrenic Patients Treated with Haloperidol and Olanzapine

European Journal of Inflammation, 2009
We investigated dopamine receptor gene expression in peripheral blood mononuclear cells of schizophrenic patients before and after treatment. Also dopamine receptor genes expression profile was compared in two treatment groups including haloperidol and ...
G.H. Shariati, G. Ahangari MT, Ph.D., M.R. Asadi, F. Poyafard, H.R. Ahmadkhaniha   +4 more
doaj   +1 more source

Peripheral blood mononuclear cells cryopreservation and transportation

JOURNAL OF BONE MARROW TRANSPLANTATION AND CELLULAR THERAPY, 2022
Chimeric antigen receptor-T (CAR-T) cells have emerged as a treatment option for patients with hematologic malignancies. Usually, their manufacture has been carried out by specialized and centralized laboratories. A useful strategy, which allows a better logistical organization, is the peripheral blood mononuclear cells (PBMC) cryopreservation and ...
Karen De Lima Prata, Andrea Tiemi Kondo
openaire   +1 more source

Human Immunodeficiency Virus-Infected Individuals Contain Provirus in Small Numbers of Peripheral Mononuclear Cells and at Low Copy Numbers [PDF]

, 1990
In human immunodeficiency virus (HIV)-infected individuals, the proportion of circulating mononuclear cells (PBMCs) which carry HIV provirus and the number of HIV proviral sequences per infected PBMC have been matters for conjecture.
LUDLAM, CA, Leigh Brown, AJ, BISHOP, JO, SIMMONDS, P, BALFE, P, PEUTHERER, JF   +5 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source