Results 71 to 80 of about 298,696 (311)

Peripheral Blood Mononuclear Cells as a Laboratory to Study Dementia in the Elderly [PDF]

BioMed Research International, 2014
The steady and dramatic increase in the incidence of Alzheimer’s disease (AD) and the lack of effective treatments have stimulated the search for strategies to prevent or delay its onset and/or progression. Since the diagnosis of dementia requires a number of established features that are present when the disease is fully developed, but not always in ...
B. Arosio, C. D'Addario, C. Gussago, M. Casati, E. Tedone, E. Ferri, P. Nicolini, P. D. Rossi, M. Maccarrone, D. Mari   +9 more
openaire   +2 more sources

Vasculogenically conditioned peripheral blood mononuclear cells inhibit mouse immune response to induced pluripotent stem cell-derived allogeneic cardiac grafts.

PLoS ONE, 2019
Allogeneic transplantation of induced pluripotent stem cell (iPSC)-derived cardiomyocytes is apromising treatment for cardiac diseases, although immune rejection by the recipient poses a concern. In this study, we aimed to investigate whether concomitant
Noriyuki Kashiyama, Shigeru Miyagawa, Satsuki Fukushima, Takuji Kawamura, Ai Kawamura, Shohei Yoshida, Yuki Nakamura, Akima Harada, Haruchika Masuda, Koichi Toda, Takayuki Asahara, Yoshiki Sawa   +11 more
doaj   +1 more source

Peripheral cytokine responses to Trichuris muris reflect those occurring locally at the site of infection [PDF]

, 2000
The study of human cellular immune responses to parasite infection under field conditions is very complex. Often, the only practical site from which to sample the cellular responses is the peripheral blood.
Betts, Catherine, Taylor, Matthew D, Taylor, Matthew D., Kathryn J. Else, Matthew D. Taylor, Betts, Catherine J., Else, Kathryn, Else, Kathryn J., Catherine J. Betts   +8 more
core   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

MicroRNA-146a induces immune suppression and drug-resistant colorectal cancer cells

Tumor Biology, 2017
Recent studies underline the involvement of microRNAs in cancer development through induction of immune suppression milieu and evolution of drug resistance. The goal of this study was to evaluate the effects of miR-146a on regulatory T cells’ frequencies,
Samaneh Khorrami, Ahmad Zavaran Hosseini, Seyed Javad Mowla, Masoud Soleimani, Naser Rakhshani, Reza Malekzadeh   +5 more
doaj   +1 more source

Secretome of peripheral blood mononuclear cells enhances wound healing.

PLoS ONE, 2013
Non-healing skin ulcers are often resistant to most common therapies. Treatment with growth factors has been demonstrated to improve closure of chronic wounds.
Michael Mildner, Stefan Hacker, Thomas Haider, Maria Gschwandtner, Gregor Werba, Caterina Barresi, Matthias Zimmermann, Bahar Golabi, Erwin Tschachler, Hendrik Jan Ankersmit   +9 more
doaj   +1 more source

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

In Vitro Study of Immune Properties of New Lactobacilli Isolates from Pheasant Gut

Folia Veterinaria, 2020
The goal of this paper was to study the effect of Lactobacillus reuteri B1/1, B2/1 and B6/1 on the relative expression of selected interleukins (IL-1β, IL-15), macrophage inflammatory protein (MIP-1β), and the relative percentage of T lymphocyte ...
Karaffová V., Revajová V., Nemcová R., Ševčíková Z., Levkutová M., Levkut M.   +5 more
doaj   +1 more source

Studies investigating peripheral blood derived cells that express the high affinity receptor for immunoglobulin E (Fc?RI) In Allergic Disorders [PDF]

, 2008
It is just forty years since the identification of immunoglobulin E (IgE) as the reagin responsible for allergen induced immediate hypersensitivity reactions.
Sihra, Bhupinder Singh
core  

P2Y6 receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells [PDF]

, 2014
This work is supported the British Heart Foundation [grant number PG/13/22/ 30077]. Deposited in PMC for immediate release.The chemokine CCL2 serves to target circulating monocytes and other leukocytes to tissue during innate immune responses, and ...
Campwala, H., Fountain, Samuel J., Sexton, D. W., Campwala, Hinnah, Fountain, SJ, Crossman, David C., Sexton, Darren W., Campwala, H, Crossman, D. C., Fountain, S. J., Sexton, DW, Crossman, DC   +11 more
core   +1 more source