Results 91 to 100 of about 298,696 (311)

Peripheral blood mononuclear cell proteome profile in Behçet’s syndrome

Rheumatology International, 2019
Behçet's syndrome (BS) is a systemic inflammatory disorder with unknown etiology. Investigation of proteome profiles of disease specific cells facilitates our understanding of the processes and related molecular pathways, especially in disorders like BS with complex inheritance pattern and clinical heterogeneity.
Asli Kirectepe Aydin, Yeşim Özgüler, Didar Uçar, Murat Kasap, Gürler Akpınar, Emire Seyahi, Eda Tahir Turanli   +6 more
openaire   +4 more sources

Assessing individual differences in genome-wide gene expression in human whole blood: reliability over four hours and stability over 10 months. [PDF]

, 2009
Studying the causes and correlates of natural variation in gene expression in healthy populations assumes that individual differences in gene expression can be reliably and stably assessed across time. However, this is yet to be established.
Plomin, Robert, Plomin, R., Meaburn, Emma L., Craig, Ian W., Craig, IW, Plomin, R, Fernandes, Cathy; id_orcid, Schalkwyk, LC, Craig, I.W., Schalkwyk, L.C., Fernandes, C, Fernandes, C., Meaburn, EL, Schalkwyk, Leonard C.   +13 more
core   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Bone marrow mononuclear cells and acute myocardial infarction [PDF]

, 2012
PMCID: PMC3340546This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Martin, J, Mozid, A, Arnous, S, Mathur, A   +3 more
core   +1 more source

A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
Chiara Veredice, Chiara Arpaia, Ilaria Contaldo, Anna Capasso, Donato Rigante   +4 more
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Type I interferon receptor in peripheral blood mononuclear cells may predict response to intra-arterial 5-fluorouracil + interferon therapy for advanced hepatocellular carcinoma

Hepatic Medicine: Evidence and Research, 2011
Yasuyuki Tomiyama1, Naoko Yoshioka1, Yoshiaki Yanai2,3, Tomoya Kawase1, Sohji Nishina1, Yuichi Hara1, Koji Yoshida1, Keiko Korenaga1, Masaaki Korenaga1, Keisuke Hino11Department of Hepatology and Pancreatology, Kawasaki Medical University, Kurashiki ...
Korenaga K, Yoshida K, Hara Y, Nishina S, Kawase T, Yanai Y, Yoshioka N, Tomiyama Y, Korenaga M, Hino K   +9 more
doaj  

The Therapeutic Potential of the Preconditioned Peripheral Blood Mononuclear Cells on Sciatic Nerve Injury in a Diabetic Rat Model [PDF]

The Egyptian Journal of Histology
Introduction: The modern medicine has witnessed immense implementation of cell-based approaches for many health issues. The therapeutic potential of the peripheral blood mononuclear cells was explicit chiefly after priming by activated platelet ...
noha Elswaidy, Hend Abd El Halim, Nema Soliman, Amira Adly Kassab, Darwish Badran   +4 more
doaj   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Gene-expression profiling of peripheral blood mononuclear cells in sepsis

Critical Care Medicine, 2009
It has been shown that gene-expression profiling of circulating neutrophils could identify signature genes of sepsis. However, whether similar transcriptional changes occurred in peripheral blood mononuclear cells (PBMC) was not known. Using microarray technology, we performed gene-expression profiling of PBMC to identify signature genes that ...
Tang, BMP, McLean, AS, Dawes, IW, Huang, SJ, Lin, RCY   +4 more
openaire   +3 more sources