Results 101 to 110 of about 298,696 (311)

Human peripheral blood mononuclear cells (PBMCs, uATAC-seq) [PDF]

, 2018
uATAC-seq for human peripheral blood mononuclear cells ...
Anja Mezger (698203), Sandy Klemm (5659817)   +1 more
core   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Varicella-Zoster viruses associated with post-herpetic neuralgia induce sodium current density increases in the ND7-23 Nav-1.8 neuroblastoma cell line [PDF]

, 2013
Post-herpetic neuralgia (PHN) is the most significant complication of herpes zoster caused by reactivation of latent Varicella-Zoster virus (VZV). We undertook a heterologous infection in vitro study to determine whether PHN-associated VZV isolates ...
Rowan, EG, Kennedy, PGE, Breuer, J, Scott Fiona, Peter G E Kennedy, Esther Grinfeld, Breuer, J., Rowan, E.G., Kennedy Peter G. E., Breuer, Judith, Paul Montague, Fiona Scott, Ashrafi, GH, Ashrafi, G.H., Judith Breuer, Rowan Edward G., Scott, F., Ashrafi G. H., Edward G Rowan, Kennedy, P. G. E., Grinfeld, E, Grinfeld Esther, Rowan, Edward, Montague, P, Montague Paul, Grinfeld, E., Breuer Judith, G H Ashrafi, Kennedy, P.G.E., Montague, P., Scott, F   +30 more
core   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Sufficiently activated mature natural killer cells derived from peripheral blood mononuclear cells substantially enhance antitumor activity

Immunity, Inflammation and Disease
Background Peripheral blood‐derived natural killer (NK) cells spontaneously lyse tumor cells without prior sensitization. However, NK cells in peripheral blood (PBNK cells) are in a resting state and exhibit inhibitory phenotypes and impaired ...
Chuanling Liu, Yingying Li, Yanrong Li, Meng Hu, Haiyan Wang, Shasha Lu, Zhao Li, Dilinuer Dilimulati, Shunchang Jiao, Shelian Lu, Weihong Zhao   +10 more
doaj   +1 more source

Sequence variability of Borna disease virus open reading frame II found in human peripheral blood mononuclear cells [PDF]

, 1996
A cDNA fragment of the Borna disease virus (BDV) open reading frame II (ORF-II), which encodes a 24-kDa phosphoprotein (p24 [P protein]), was amplified from total RNA of peripheral blood mononuclear cells (PBMC) from three psychiatric inpatients.
Kazuyoshi Ikuta, Masahiko Kishi, Yutaka Arimura, Yuko Shoya, Patrick K. Lai, Blood Mononuclear Cells, Mitsuaki Kakinuma   +6 more
core  

Factors affecting the infant antibody response to measles immunisation in Entebbe-Uganda. [PDF]

, 2013
BACKGROUND: Vaccine failure is an important concern in the tropics with many contributing elements. Among them, it has been suggested that exposure to natural infections might contribute to vaccine failure and recurrent disease outbreaks.
Webb, Emily L, Emily L Webb, Tweyongyere, Robert, Bukenya, Henry, Muhangi, Lawrence, Lawrence Muhangi, Swaib A Lule, Stephen Cose, Lule, Swaib A, Alice Namatovu, Alison M Elliott, Namatovu, Alice, Cose, Stephen, Dennison Kizito, Elliott, Alison M, Robert Tweyongyere, Kizito, Dennison, Henry Bukenya   +17 more
core   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Hematopoietic stem and progenitor cells are differentially mobilized depending on the duration of Flt3-ligand administration

Haematologica, 2010
Background Flt3-ligand is a cytokine that induces relatively slow mobilization of hematopoietic cells in animals and humans in vivo. This provides a time-frame to study hematopoietic stem and progenitor cell migration kinetics in detail.Design and ...
Evert-Jan F.M. de Kruijf, Henny Hagoort, Gerjo A. Velders, Willem E. Fibbe, Melissa van Pel   +4 more
doaj   +1 more source

peripheral blood mononuclear cell

Citation: 'peripheral blood mononuclear cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13553 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual
openaire   +1 more source