Results 31 to 40 of about 2,424,442 (276)

Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge [PDF]

open access: yes, 2012
Background: Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma.
Rose Markus A   +17 more
core   +1 more source

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

open access: yeseLife, 2017
Chemotherapy-induced peripheral neuropathy (CIPN) arises from collateral damage to peripheral afferent sensory neurons by anticancer pharmacotherapy, leading to debilitating neuropathic pain.
Peter M LoCoco   +5 more
doaj   +1 more source

Balance Problems for Integer Circuits [PDF]

open access: yes, 2018
We investigate the computational complexity of balance problems for {-,*}-circuits computing finite sets of natural numbers. These problems naturally build on problems for integer expressions and integer circuits studied by Stockmeyer and Meyer (1973 ...
Dose, Titus, Titus Dose
core   +1 more source

ON THE AUTOMORPHISMS OF THE NONSPLIT CARTAN MODULAR CURVES OF PRIME LEVEL [PDF]

open access: yes, 2016
We study the automorphisms of the nonsplit Cartan modular curves Xns(p) of prime level p. We prove that if p ≥ 29 all the automorphisms preserve the cusps.
VALERIO DOSE, Dose V.
core   +1 more source

Low Dose-Rate Irradiation of Gamma-Rays-Induced Cytotoxic and Genotoxic Alterations in Peripheral Erythrocytes of p53-Deficient Medaka (Oryzias latipes)

open access: yesFrontiers in Marine Science, 2021
Morphological alterations and nuclear abnormalities in fish erythrocytes have been used in many studies as bioindicators of environmental mutagens including ionizing radiation.
Alaa El-Din H. Sayed   +8 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose X-irradiation [PDF]

open access: yes, 2012
Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and ...
Seegenschmiedt, Michael H.   +26 more
core   +1 more source

A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints . [PDF]

open access: yes, 2007
Bayesian decision procedures have already been proposed for and implemented in phase I dose-escalation studies in healthy volunteers. The procedures have been based on pharmacokinetic responses reflecting the concentration of the drug in blood plasma and
Hampson, Lisa   +4 more
core   +5 more sources

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani   +7 more
wiley   +1 more source

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