Results 31 to 40 of about 671,786 (158)

Role for Drug Transporters in Chemotherapy‐Induced Peripheral Neuropathy

Clinical and Translational Science, 2021
Chemotherapy‐induced peripheral neuropathy (CIPN) is a common and dose‐limiting toxicity to widely used chemotherapeutics. Although the exact molecular mechanism of chemotherapy‐induced peripheral neuropathy remains elusive, there is consensus that it is
Tore B. Stage, Shuiying Hu, Alex Sparreboom, Deanna L. Kroetz   +3 more
doaj   +1 more source

Patterns of locoregional failure following post-operative intensity-modulated radiotherapy to oral cavity cancer: quantitative spatial and dosimetric analysis using a deformable image registration workflow

Radiation Oncology, 2017
Background We sought to identify spatial/dosimetric patterns of failure for oral cavity cancer patients receiving post-operative IMRT (PO-IMRT). Methods Two hundred eighty-nine OCC patients receiving PO-IMRT were retrospectively reviewed from 2000 to ...
Abdallah S. R. Mohamed, Andrew J. Wong, Clifton D. Fuller, Mona Kamal, Gary B. Gunn, Jack Phan, William H. Morrison, Beth M. Beadle, Heath Skinner, Stephen Y. Lai, Sean R. Quinlan-Davidson, Abdelaziz M. Belal, Ahmed G. El-Gowily, Steven J. Frank, David I. Rosenthal, Adam S. Garden   +15 more
doaj   +1 more source

Monte Carlo Study of Fetal Dosimetry Parameters for 6 MV Photon Beam

Journal of Medical Signals and Sensors, 2013
Because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. Fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses ...
Maryam Atarod, Parvaneh Shokrani
doaj  

Assessment of peripheral dose as a function of distance and depth from cobalt-60 beam in water phantom using TLD-100

Journal of the Egyptian National Cancer Institute
Background Innovations in cancer treatment have contributed to the improved survival rate of cancer patients. The cancer survival rates have been growing and nearly two third of those survivors have been exposed to clinical radiation during their ...
Habib Ahmad, Javaid Ali, Khalil Ahmad, Ghufran Biradar, Ashfaq Zaman, Yasir Uddin, Muhammad Sohail, Shahid Ali   +7 more
doaj   +1 more source

Study of Indicators for Early and Rapid Diagnosis of Radiation Injury Is the Most Important in Patients With Cancer During Radiotherapy

Dose-Response, 2020
Objective: To establish a complete technical solution for the radiation biological dose estimation, to enable prediction of individuals’ response to radiotherapy (RT), and to control treatment dose for reduced irradiation injury and promote repair; and ...
Gang Liu, Li-Mei Niu, Li-Qin Wang, Ye Li, Xiao-Qin Wu, Yin-Yin Liu, Rong Zhang   +6 more
doaj   +1 more source

Leg oedema due to low-dose risperidone during maintenance monotherapy of schizophrenia

Psychiatry and Clinical Psychopharmacology, 2018
Drug-related peripheral leg oedema is most commonly associated with steroids, nonsteroidal anti-inflammatory, antihypertensives, and immunosuppressive agents.
Serhat Tunç, Hamit Serdar Başbuğ
doaj   +1 more source

Influence of dosing times on cisplatin-induced peripheral neuropathy in rats [PDF]

BMC Cancer, 2016
Although cis-diamminedichloro-platinum (CDDP) exhibits strong therapeutic effects in cancer chemotherapy, its adverse effects such as peripheral neuropathy, nephropathy, and vomiting are dose-limiting factors. Previous studies reported that chronotherapy decreased CDDP-induced nephropathy and vomiting.
Seto, Yoshihiro, Okazaki, Fumiyasu, Horikawa, Keiji, Zhang, Jing, Sasaki, Hitoshi, To, Hideto   +5 more
openaire   +2 more sources

Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism. [PDF]

PLoS ONE, 2013
Ghrelin is an endogenous regulator of energy homeostasis synthesized by the stomach to stimulate appetite and positive energy balance. Similarly, the endocannabinoid system is part of our internal machinery controlling food intake and energy expenditure.
Francisco Alen, Inmaculada Crespo, María Teresa Ramírez-López, Nadine Jagerovic, Pilar Goya, Fernando Rodríguez de Fonseca, Raquel Gómez de Heras, Laura Orio   +7 more
doaj   +1 more source

Consequences of peripheral chemoreflex inhibition with low‐dose dopamine in humans

The Journal of Physiology, 2014
Key points Low‐dose dopamine reduces the ventilatory response to acute hypoxia both in animal and in human studies. In this study we show that low‐dose dopamine ...
Niewinski, Piotr, Tubek, Stanislaw, Banasiak, Waldemar, Paton, Julian F R, Ponikowski, Piotr   +4 more
openaire   +5 more sources

Effects of Low Dose Neutron-Gamma Field on Cell Cycle and Damage of Human Lymphocytes

Dose-Response
Purpose: The aim is to investigate the response of peripheral blood lymphocytes to a low-dose neutron-gamma field. Methods: The human peripheral blood was exposed to low-dose neutron-gamma radiation ex vivo.
Jinghong Fu, Guangfen Du, Haiqing Wang, Chenxing Liao, Yuyan Zhang, Weiguo Li   +5 more
doaj   +1 more source