Results 21 to 30 of about 2,424,442 (276)
The peripheral vascular effects of diltiazem‐dose‐response characteristics. [PDF]
British Journal of Clinical Pharmacology, 1985 The acute effects of increasing doses of diltiazem on peripheral blood flow were observed in six subjects. Each subject received, in random order, a single oral dose of placebo or diltiazem 60, 120 or 180 mg. Supine heart rate, blood pressure, skin temperature, digital systolic pressure, forearm and digital blood flow were recorded before and at 1, 2 ...
M B, Finch, G D, Johnston
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Trials, 2023 Background Peripheral neuropathy is a common dose-limiting side effect of paclitaxel. To date, there is no effective strategy to prevent paclitaxel-induced peripheral neuropathy.
Praful Pandey +9 more
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Radioprotective Effect of Two Kinds of Protein Peptides in Ray-irradiated Mice
Shipin gongye ke-ji, 2022 Objective: To investigate the radioprotective effect of jackfruit protein peptide and collagen peptide with pleasant mouthfeel in many bioactive peptides in 60Co γ ray-irradiated mice.
Aiqing LIU +5 more
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Multiple-dose pharmacokinetics of telithromycin in peripheral soft tissues [PDF]
International Journal of Antimicrobial Agents, 2009 Based on clinicians' expectations of high concentrations of telithromycin (TEL) in tissues, combined with its excellent in vitro antimicrobial characteristics, TEL is casually considered as a potential therapeutic option for the therapy of minor cases of soft tissue or bite-wound infections.
Traunmüller, Friederike +4 more
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IEEE Access, 2019 CyberKnife is a robotic stereotactic body radiotherapy (SBRT) system that precisely delivers large radiation doses to a target. Tissue heterogeneity and shape can be problems.
Yu-Jie Huang +8 more
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Cisplatin-lnduced peripheral neurotoxicity is dependent on total-dose intensity and single-dose intensity [PDF]
Cancer, 1992 The authors prospectively evaluated the effects of three different schedules of cisplatin (DDP) administration in 60 patients with advanced epithelial ovarian cancer. The individual total dose of DDP was 450 mg/m2 in all three groups, and the anti-cancer response at the end of treatment was similar for the different regimens.
Cavaletti, GA +6 more
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Journal of Translational Medicine, 2008 Background LXRs (Liver X Receptor α and β) are nuclear receptors that act as ligand-activated transcription factors. LXR activation causes upregulation of genes involved in reverse cholesterol transport (RCT), including ABCA1 and ABCG1 transporters, in ...
Mounts William M +18 more
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Dose prescription with spatial uncertainty for peripheral lung
Journal of Applied Clinical Medical Physics, 2018 AbstractCurrent clinical practice is to prescribe to 95% of the planning target volume (PTV) in 4D stereotactic body radiotherapy (SBRT) for lung. Frequently the PTV margin has a very low physical density so that the internal target volume (ITV) receives an unnecessarily high dose. This study investigates the alternative of prescribing to the ITV while
Bedford, JL, Blasiak-Wal, I, Hansen, VN
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Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients
Brazilian Journal of Medical and Biological Research, 2005 FTY720 is a new and effective immunosuppressive agent, which produces peripheral blood lymphopenia through a lymphocyte homing effect. We investigated the relationship between the dose of FTY720 or blood concentration (pharmacokinetics, PK) and ...
S.I. Park +7 more
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Radiation Oncology, 2021 Objective To evaluate the influence of target dose heterogeneity on normal tissue dose sparing for peripheral lung tumor stereotactic body radiation therapy (SBRT).
Zhigong Wei +9 more
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