Results 201 to 210 of about 118,363 (344)

Conveniently templated porous chitosan conduit with highly aligned luminal wall and seamless side wall for peripheral nerve regeneration

, 2016
Guicai Li, Yumin Yang, Xiaosong Gu
openalex   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

Advanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou, Mengxuan Bian, Lingyu Wei, Binghuang Yao, Qi Chen, Lan Xiao, Jing He, Jian Zhang, Yulin Li, Libo Jiang   +9 more
wiley   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

Advanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng, Zhaowei Zhang, Zezhou Fu, Qingqing Wang, Siwen Zhang, Tingyu Zhang, Meifei Zhu, Shunwu Fan, Youqing Shen, Jiajia Xiang, Xin Liu   +10 more
wiley   +1 more source

Functional assessment of local versus systemic adipose-derived stromal cell therapy in rodent peripheral nerve regeneration. [PDF]

Front Neurol
Targosinski S, Wieser N, Klein HJ, Kamat P, Barth AA, Rushing EJ, Kim BS, Plock JA, Schweizer R.   +8 more
europepmc   +1 more source

Pathways regulating modality-specific axonal regeneration in peripheral nerve

, 2015
Matthew D. Wood, Susan E. Mackinnon
openalex   +2 more sources

Enhancing peripheral nerve regeneration through NaOH-based decellularization of human nerve tissue. [PDF]

Bioeng Transl Med
Kim S, Park SH, Mun J, Jung SW, Lee WJ, Lee DW, Lee KW.   +6 more
europepmc   +1 more source

[Preparation and properties of fiber-based conductive composite scaffolds for peripheral nerve regeneration].

, 2019
Wufei Dai, Jiaqi Shi, Sha Liu, Ziqi Xu, Yi-jin Shi, Yahong Zhao, Yumin Yang   +6 more
openalex   +2 more sources

Surface Modification of Poly(L-lactic acid) Nanofiber with Oligo(D-lactic acid) Bioactive-Peptide Conjugates for Peripheral Nerve Regeneration [PDF]

, 2011
Sachiro Kakinoki, Sho Uchida, Tomo Ehashi, Akira Murakami, Tetsuji Yamaoka   +4 more
openalex   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Modulating Schwann cell behavior via functional nerve guidance conduits for enhanced peripheral nerve regeneration. [PDF]

NPJ Regen Med
Yang K, Yang S, Teng X, He X, Sun T, Chen H.   +5 more
europepmc   +1 more source