Results 71 to 80 of about 148,079 (169)
Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer [PDF]
Heliyon, Volume 10, Issue 13, e33932, July 15, 2024ICAM-1 (intercellular adhesion molecule 1) and MPZ (myelin protein zero) are thought to be a factor in the integrity of nerve tissues. In this report, we attempted to trace the expression of ICAM-1, responsible for cell-to-cell adhesion, and of MPZ, the main constituent of myelin sheath, in malignant tissues of the sciatic nerve (SN) in inbred male ...
arxiv +1 more source
Theranostics, 2019 Background: Peripheral nerve regeneration requires coordinated functions of neurotrophic factors and neuronal cells. CRISPR activation (CRISPRa) is a powerful tool that exploits inactive Cas9 (dCas9), single guide RNA (sgRNA) and transcription activator ...
Mu-Nung Hsu +9 more
semanticscholar +1 more source
Extracting impedance changes from a frequency multiplexed signal during neural activity in sciatic nerve of rat: preliminary study in-vitro [PDF]
, 2019 Objective: Establish suitable frequency spacing and demodulation steps to use when extracting impedance changes from frequency division multiplexed (FDM) carrier signals in peripheral nerve. Approach: Experiments were performed in-vitro on cadavers immediately following euthanasia.
arxiv +1 more source
Photobiomodulation Therapy (PBMT) in Peripheral Nerve Regeneration: A Systematic Review
Bioengineering, 2018 Photobiomodulation therapy (PBMT) has been investigated because of its intimate relationship with tissue recovery processes, such as on peripheral nerve damage.
Marcelie Priscila de Oliveira Rosso +5 more
semanticscholar +1 more source
Investigation of ephaptic interactions in peripheral nerve of sheep using 6 kHz subthreshold currents [PDF]
arXiv, 2019 The objective of this work was to determine whether application of subthreshold currents to the peripheral nerve increases the excitability of the underlying nerve fibres, and how this increased excitability would alter neural activity as it propagates through the subthreshold currents. Experiments were performed on two Romney cross-breed sheep in vivo,
arxiv
Biomimetic neural scaffolds: a crucial step towards optimal peripheral nerve regeneration.
Biomaterials Science, 2018 Peripheral nerve injury is a common disease that affects more than 20 million people in the United States alone and remains a major burden to society.
Jian Du +4 more
semanticscholar +1 more source
iScienceSummary: Fibrotic scar is one of the main impediments to axon regeneration following spinal cord injury (SCI). In this study, we found that CD44 was upregulated during the formation of fibrotic scar, and blocking CD44 by IM7 caused downregulation of ...
Jin Guo +9 more
doaj
Inflammation in the Peripheral Nervous System after Injury
BiomedicinesNerve injury is a common condition that occurs as a result of trauma, iatrogenic injury, or long-lasting stimulation. Unlike the central nervous system (CNS), the peripheral nervous system (PNS) has a strong capacity for self-repair and regeneration ...
Dandan Gu +7 more
doaj +1 more source
Annals of Translational Medicine, 2019 Background Oxidative stress has been recognized to play a crucial role in the pathogenesis of peripheral nerve injury. Isoquercitrin (quercetin-3-glucoside) is a flavonoid that exhibited many biological activities, including anti-oxidative effect ...
Jiaying Qiu +9 more
semanticscholar +1 more source
Potential of Stem-Cell-Induced Peripheral Nerve Regeneration: From Animal Models to Clinical Trials
LifePeripheral nerve injury has become an increasingly prevalent clinical concern, causing great morbidity in the community. Although there have been significant advancements in the treatment of peripheral nerve damage in recent years, the issue of long-term
Taylor M. Wynne +7 more
doaj +1 more source