Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen +15 more
wiley +1 more source
Magnetic Resonance Imaging of the Peripheral Nerves and Fascicles of the Knee Using Double Echo Steady State Sequence at 7 Tesla. [PDF]
Chen P +14 more
europepmc +1 more source
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
A Charcot-Marie-Tooth Disease Type 1J Case With Diffuse Thickening of Peripheral Nerves. [PDF]
Zhu X +5 more
europepmc +1 more source
Imaging Peripheral Nerves In Vivo with CT Neurogram Using Novel 2,4,6-Tri-Iodinated Lidocaine Contrast Agent. [PDF]
Tang R +4 more
europepmc +1 more source
Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves: The Maastricht study. [PDF]
van der Heide FCT +17 more
europepmc +1 more source
Tendon Transfer Procedures for Correction of Foot Drop Due to Injury to the Peripheral Nerves or Muscles. [PDF]
Lauer H +7 more
europepmc +1 more source
Glycoprotein 130 improves repressor element‑1 silencing transcription factor‑related axon regenerative capacity in peripheral nerves with aging. [PDF]
Kawakita S +10 more
europepmc +1 more source
Managing Major Peripheral Nerves in Forearm-Level Amputations With TMR and RPNI: What's the Best Recipe? [PDF]
Rees AB +4 more
europepmc +1 more source
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Peripheral Nerve Abnormalities
Ultrasound Clinics, 2007As experience is gained, ultrasound (US) continues to identify an increasing number of nerves and related pathologic conditions. High-resolution US provides cost-effective, accurate morphologic information regarding a variety of nerve abnormalities including inherited disorders and developmental anomalies, nerve involvement in medical diseases ...
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