Peripheral Nerve Injuries and Regeneration
Peripheral nerves are a system consisting of various nerve fibers named according to the functions they stimulate in the target organ that provides motor and sensory stimulation between the central nervous system and peripheral organs. Peripheral nerves,
İşınsu ALKAN+2 more
doaj +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR+6 more
core
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter+2 more
core +1 more source
Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier [PDF]
Schwann cells (SC) are characterized by a remarkable plasticity that enables them to promptly respond to nerve injury promoting axonal regeneration. In peripheral nerves after damage SC convert to a repair-promoting phenotype activating a sequence of ...
Ciraci, Viviana+9 more
core +2 more sources
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
An effect of wrapping peripheral nerve anastomosis with pedicled muscle flap on nerve regeneration in experiment [PDF]
Despite intrinsic capacity of peripheral nerves to regenerate, functional outcomes of peripheral nerves injury remain poor. Nerve ischemia, intra-/perineurial fibrosis and neuroma formation contribute a lot to that.
Naumenko L.Yu.+2 more
doaj
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback [PDF]
In developing limb skin, peripheral nerves are required for arterial differentiation, and guide the pattern of arterial branching. In vitro experiments suggest that nerve-derived VEGF may be important for arteriogenesis, but its role in vivo remains ...
Anderson, David J.+4 more
core +1 more source
Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao+34 more
wiley +1 more source
Schwannomas of the female genital tract are extremely uncommon. They are usually benign, and simple excision is the adequate treatment. The case of a 57-year-old woman with a cellular schwannoma of the vagina is described, in addition to a summarized ...
Joana Aidos+5 more
doaj +1 more source
Peripheral Nerve Lesions [PDF]
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openaire +2 more sources