Results 61 to 70 of about 923,557 (299)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Retrospective Analysis of 20 Patients Affected by Schwannomas in the Upper and Lower Limbs [PDF]

Revista Brasileira de Ortopedia
Objective To analyze the epidemiological profile and evolution of 20 patients diagnosed with upper- and lower-limb schwannomas. Methods A group of patients was defined for a retrospective evaluation comprising the period between February 2002 and June ...
José Antonio Galbiatti, Gabriel Rodrigues dos Santos Milhomens, Lara Giovanetti Bertozzo, Letícia Escames, Pedro de Alcântara Milhomens Neto, Marilia Gabriela Palacio Galbiatti   +5 more
doaj   +4 more sources

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Diffusion tensor imaging of peripheral nerves

, 2015
Diffusion tensor imaging (DTI) is a powerful MR imaging technique that can be used to probe the microstructural environment of highly anisotropic tissues such as peripheral nerves.
Awdeh, Haitham, Andreisek, Gustav, Naraghi, Ali M, Chhabra, Avneesh, Wadhwa, Vibhor, Wadhwa V, Andreisek G, Naraghi AM, Awdeh H, Chhabra A   +9 more
core   +1 more source

Analysis of periodic oscillations of APDs in reaction diffusion waves with nonlinear diffusion in tissues with peripheral nerve injury (PNI) [PDF]

, 2023
Millions of people suffer from peripheral nerve injury every year. Previous works have predominantly focused on surgical means of injury treatment without sufficient attention to studying distinct mechanisms of electrical conduction in small peripheral ...
Oni, Olumide T., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Sciatic neurotmesis and periostitis ossificans progressiva due to a traumatic/unexpected glass injury: a case report [PDF]

Journal of Yeungnam Medical Science
Peripheral nerves may be affected or injured for several reasons. Peripheral nerve damage can result from trauma, surgery, anatomical abnormalities, entrapment, systemic diseases, or iatrogenic injuries. Trauma and iatrogenic injuries are the most common
Berkay Yalçınkaya, Hasan Ocak, Ahmet Furkan Çolak, Levent Özçakar   +3 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Strain stiffening of peripheral nerves subjected to longitudinal extensions in vitro [PDF]

, 2020
The mechanical response of peripheral nerves is crucial to understand their physiological and pathological conditions. However, their response to external mechanical solicitations is still partially unclear, since peripheral nerves could behave in a ...
Giannessi E., Sergi P. N., Stornelli M. R.   +2 more
core   +1 more source

Microsurgery and nerve regeneration: a technical note on intercostal nerves of the swine model

Egyptian Journal of Neurosurgery
Purpose The aim of this article is to present a novel large animal model for studying peripheral nerve regeneration. Large animals present a distinct superiority in mimicking clinical scenarios found in humans.
Nikolaos Giannakopoulos Theodorou, Sotirios Botaitis, Theodosios Birbilis   +2 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source