Peripheral Nerve Injuries and Regeneration
Peripheral nerves are a system consisting of various nerve fibers named according to the functions they stimulate in the target organ that provides motor and sensory stimulation between the central nervous system and peripheral organs. Peripheral nerves,
İşınsu ALKAN+2 more
doaj +1 more source
The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR+6 more
core
ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]
Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Anderson, PN+6 more
core +3 more sources
Iron role paradox in nerve degeneration and regeneration [PDF]
Iron accumulates in the neural tissue during peripheral nerve degeneration. Some studies have already been suggested that iron facilitates Wallerian degeneration (WD) events such as Schwann cell de-differentiation. On the other hand, intracellular iron levels remain elevated during nerve regeneration and gradually decrease.
arxiv +1 more source
“Long-term stability of stimulating spiral nerve cuff electrodes on human peripheral nerves”
BackgroundElectrical stimulation of the peripheral nerves has been shown to be effective in restoring sensory and motor functions in the lower and upper extremities. This neural stimulation can be applied via non-penetrating spiral nerve cuff electrodes,
Breanne P. Christie+6 more
semanticscholar +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Background. Multifocal motor neuropathy (MMN) is а chronical dysimmune disease, which can be treated with intravenous human immunoglobulin (IVIG).Objectives.
S. S. Nikitin+2 more
doaj +1 more source
An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering [PDF]
yesCurrent nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy and physiology of these nerves ...
Garner, P.E.+5 more
core +3 more sources
Toward peripheral nerve mechanical characterization using Brillouin imaging spectroscopy [PDF]
SIGNIFICANCE: Peripheral nerves are viscoelastic tissues with unique elastic characteristics. Imaging of peripheral nerve elasticity is important in medicine, particularly in the context of nerve injury and repair.
Berezin, Mikhail Y+4 more
core +2 more sources
Simulating optical coherence tomography for observing nerve activity: a finite difference time domain bi-dimensional model [PDF]
We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference signal in post processing, it is possible to reduce the computational time required by the simulations and, thus, to ...
arxiv +1 more source