Results 1 to 10 of about 783,564 (214)

Inflammation in the Peripheral Nervous System after Injury [PDF]

Biomedicines
Nerve injury is a common condition that occurs as a result of trauma, iatrogenic injury, or long-lasting stimulation. Unlike the central nervous system (CNS), the peripheral nervous system (PNS) has a strong capacity for self-repair and regeneration ...
Dandan Gu, Yiming Xia, Zihan Ding, Jiaxi Qian, Xi Gu, Huiyuan Bai, Maorong Jiang, Dengbing Yao   +7 more
doaj   +2 more sources

Women in the field of multiple sclerosis: How they contributed to paradigm shifts

Frontiers in Molecular Neuroscience, 2023
History is full of women who made enormous contributions to science. While there is little to no imbalance at the early career stage, a decreasing proportion of women is found as seniority increases.
Andreia Barateiro, Andreia Barateiro, Catarina Barros, Maria V. Pinto, Ana Rita Ribeiro, Ainhoa Alberro, Ainhoa Alberro, Adelaide Fernandes, Adelaide Fernandes   +8 more
doaj   +1 more source

Axonal Transport and Local Translation of mRNA in Neurodegenerative Diseases

Frontiers in Molecular Neuroscience, 2021
Since neurons have long neurites including axons, it is crucial for the axons to transport many intracellular substances such as proteins and mitochondria in order to maintain their morphology and function.
Seiichi Nagano, Seiichi Nagano, Toshiyuki Araki   +2 more
doaj   +1 more source

The complex relationship between obesity and neurodegenerative diseases: an updated review

Frontiers in Cellular Neuroscience, 2023
Obesity is a global epidemic, affecting roughly 30% of the world’s population and predicted to rise. This disease results from genetic, behavioral, societal, and environmental factors, leading to excessive fat accumulation, due to insufficient energy ...
Alexandre Neto, Adelaide Fernandes, Adelaide Fernandes, Andreia Barateiro, Andreia Barateiro   +4 more
doaj   +1 more source

Natalizumab affects T-cell phenotype in multiple sclerosis: implications for JCV reactivation [PDF]

, 2016
The anti-CD49d monoclonal antibody natalizumab is currently an effective therapy against the relapsing-remitting form of multiple sclerosis (RRMS). Natalizumab therapeutic efficacy is limited by the reactivation of the John Cunningham polyomavirus (JCV ...
A Bellizzi, A Laroni, A Petrovic, Ada Francia, Alessandra D’Abramo, Alessandra Oliva, Anna Bellizzi, B Engelhardt, BL Padgett, C Bozic, C Tornatore, Claudia D’Agostino, Claudio Maria Mastroianni, D Jing, E Pucci, Elena Anzivino, EM Frohman, EM Johnson, Enrico Millefiorini, EO Major, EO Major, F Serana, F Taguchi, G Defer, H Bonig, K Khalili, L Börnsen, L Gorelik, LJ Marshall, M Niino, Manuela Morreale, Marco Iannetta, Maria Antonella Zingaropoli, Maria Rosa Ciardi, MC Monaco, ME Hemler, P Maenetje, RA Rudick, RM Ransohoff, Robert Shin Fujinami, RR Lobb, S Beltrami, SA Houff, SA Sadiq, Sara Lo Menzo, Simona Pontecorvo, T Van Loy, Valeria Pietropaolo, Vincenzo Vullo, WJ Atwood, Y Chen, Ö Yaldizli   +51 more
core   +6 more sources

First Family of MATR3-Related Distal Myopathy From Italy: The Role of Muscle Biopsy in the Diagnosis and Characterization of a Still Poorly Understood Disease

Frontiers in Neurology, 2021
Mutations in the MATR3 gene are associated to distal myopathy with vocal cord and pharyngeal weakness (VCPDM), as well as familiar and sporadic motor neuron disease.
Michele Cavalli, Rosanna Cardani, Laura Valentina Renna, Mauro Toffetti, Luisa Villa, Giovanni Meola   +5 more
doaj   +1 more source

Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair [PDF]

, 2016
Peripheral nerve injury continues to pose a clinical hurdle despite its frequency and advances in treatment. Unlike the central nervous system, neurons of the peripheral nervous system have a greater ability to regenerate.
Bhangra, KS, Busuttil, F, Phillips, JB, Rahim, AA   +3 more
core   +9 more sources

Immunohistochemical demonstration of specific antigens in the human brain fixed in zinc-ethanol-formaldehyde

European Journal of Histochemistry, 2015
Tissue fixation is critical for immunohistochemistry. Recently, we developed a zinc-ethanol-formalin fixative (ZEF), and the present study was aimed to assess the applicability of the ZEF for the human brain histology and immunohistochemistry and to ...
D.E. Korzhevskii, E.G. Sukhorukova, O.V. Kirik, I.P. Grigorev   +3 more
doaj   +1 more source

Miller Fisher syndrome, Bickerstaff brainstem encephalitis and Guillain-Barré syndrome overlap with persistent non-demyelinating conduction blocks: a case report

BMC Neurology, 2018
Background Miller Fisher syndrome (MFS) and Bickerstaff’s Brainstem Encephalitis (BBE) share some clinical features and a common immunological profile characterized by anti-GQ1b antibodies.
Angela Puma, Jeanne Benoit, Sabrina Sacconi, Antonino Uncini   +3 more
doaj   +1 more source

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

, 2009
Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Bernhard Bettler, Dirig DM, Hao JX, Hosny A, Imgard Tegeder, Martina Kurejova, Nitin Agarwal, Rohini Kuner, Stefan Brugger, Vijayan Gangadharan   +9 more
core   +3 more sources