Results 111 to 120 of about 94,200 (277)

Substance P a potent prognostic indicator for canine mammary tumours- a comparative study

Journal of Veterinary and Animal Sciences
Substance P, a neurotransmitter in the central and peripheral nervous system, is considered as a biomarker of pain due to its key role in nociception. But recent researches have proved the increased expression of Substance P and its receptors in
Soumya Ramankutty, S, Anoop, Syam K. Venugopal, M. K. Narayanan, A. R. Nisha, G. Radhika   +5 more
doaj   +1 more source

Pharmaceuticals, except biologicals : 2007 [PDF]

, 2008
Current industrial report.

core  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Clinical and pathological aspects of bovine lymphoma affecting the spinal cord

Pesquisa Veterinária Brasileira
: Clinical and pathological features of bovine lymphoma involving the spinal cord were evaluated through a retrospective study of the necropsy database from 2005 to 2017.
Lauren S. Mello, Welden Panziera, Marcele B. Bandinelli, Luciana Sonne, David Driemeier, Saulo P. Pavarini   +5 more
doaj   +1 more source

Primary extracranial meningioma of the mandible [PDF]

, 2009
Meningiomas are benign tumors of mesodermal origin that arise from arachnoid cell clusters that penetrate the dura to form arachnoid villi. These neoplasms represent one of the most common neoplasms developing within the central nervous system and are ...
Cano Valdez, Ana María, Domínguez Malagón, Hugo, Montiel Hernandez, Ana Maria, Mosqueda Taylor, Adalberto   +3 more
core  

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: a pilot randomized clinical trial

São Paulo Medical Journal
CONTEXT AND OBJECTIVEOxaliplatin is one of the chemotherapy regimens most used for treating colorectal cancer. One of the main limitations to its use is induction of peripheral neuropathy.
Samuel Oliveira de Afonseca, Felipe Melo Cruz, Daniel de Iracema Gomes Cubero, Andrea Thaumaturgo Lera, Fernanda Schindler, Marcia Okawara, Luiz Fernando de Souza, Nataly Pimentel Rodrigues, Auro del Giglio   +8 more
doaj   +1 more source

T-Lymphoblastic Lymphoma with an Unusual t(8;14)(q24;q11) – Case Report [PDF]

, 2010
Cytogenetic abnormalities seen at presentation of acute lymphoblastic leukemia or lymphoblastic lymphoma (ALL/ LBL) are associated with distinct clinical and hematologic disease entities.
Ika Kardum-Skelin, Inga Mandac, Jasminka Jakelić-Piteša, Radovan Vrhovac, Ružica Lasan-Trčić, Slobodanka Ostojić Kolonić   +5 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

BRAIN ABSCESS CAUSED BY NOCARDIA ARAOENSIS IN AN IMMUNOCOMPETENT PATIENT: CASE REPORT

Brazilian Journal of Infectious Diseases
Brain abscess due to Nocardia is a rare central nervous system infection that primarily affects immunocompromised patients. The Nocardia asteroides complex accounts for most infections.
Isabel, Luciana Alves Pereira, Greyce Khoury Mansour, Aline da Silva Gonzalez   +3 more
doaj   +1 more source