Results 121 to 130 of about 17,998,872 (270)

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Radiologic Diagnosis of Toxic Injury to Spinal Cord and Peripheral Nervous System as an Immune-Mediated Complication of Antitumor Therapy

Инновационная медицина Кубани
Immunotherapy represents a significant breakthrough in modern oncology, being successfully used in the treatment of various malignant neoplasms including those at advanced metastatic stages.
A. E. Gerasyuta, E. Yu. Krivitskaya, A. E. Khakhileva, V. A. Porhanov   +3 more
doaj  

Clinical and pathological aspects of bovine lymphoma affecting the spinal cord

Pesquisa Veterinária Brasileira
: Clinical and pathological features of bovine lymphoma involving the spinal cord were evaluated through a retrospective study of the necropsy database from 2005 to 2017.
Lauren S. Mello, Welden Panziera, Marcele B. Bandinelli, Luciana Sonne, David Driemeier, Saulo P. Pavarini   +5 more
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: a pilot randomized clinical trial

São Paulo Medical Journal
CONTEXT AND OBJECTIVEOxaliplatin is one of the chemotherapy regimens most used for treating colorectal cancer. One of the main limitations to its use is induction of peripheral neuropathy.
Samuel Oliveira de Afonseca, Felipe Melo Cruz, Daniel de Iracema Gomes Cubero, Andrea Thaumaturgo Lera, Fernanda Schindler, Marcia Okawara, Luiz Fernando de Souza, Nataly Pimentel Rodrigues, Auro del Giglio   +8 more
doaj   +1 more source

Walsh & Hoyt: Peripheral Autonomic Nervous System

, 2005
The peripheral component of the autonomic nervous system provides innervation to viscera, glands, blood vessels, and smooth (nonstriated) muscle, forming the visceral portion of the nervous system.
Randy H. Kardon, MD, PhD
core  

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

BRAIN ABSCESS CAUSED BY NOCARDIA ARAOENSIS IN AN IMMUNOCOMPETENT PATIENT: CASE REPORT

Brazilian Journal of Infectious Diseases
Brain abscess due to Nocardia is a rare central nervous system infection that primarily affects immunocompromised patients. The Nocardia asteroides complex accounts for most infections.
Isabel, Luciana Alves Pereira, Greyce Khoury Mansour, Aline da Silva Gonzalez   +3 more
doaj   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

Treatment-resistant inflammatory demyelinating pseudotumor with Marburg-like features: A narrative review-based treatment approach

Journal of Research in Medical Sciences
Inflammatory demyelinating pseudotumor (IDP) mimics intracranial neoplasms in terms of both clinical presentation and imaging features. IDP with Marburg-like features represents a severe form of inflammatory demyelinating encephalomyelitis, marked by a ...
Mohammad Amin Najafi, Shakiba Houshi, Payam Riahi, Salar Nasr, Mohammad Reza Najafi   +4 more
doaj   +1 more source