Results 81 to 90 of about 195 (181)

Tiny needles, major benefits: acupuncture in child health

open access: yesBMC Pediatrics
Objective To retrospectively investigate the utilization patterns and clinical indications of acupuncture within the pediatric population in general hospitals from 2015 to 2020, including disease spectrum characteristics and relevance to pediatric ...
Xiaobin Ge   +3 more
doaj   +1 more source

Substance P a potent prognostic indicator for canine mammary tumours- a comparative study

open access: yesJournal of Veterinary and Animal Sciences
Substance P, a neurotransmitter in the central and peripheral nervous system, is considered as a biomarker of pain due to its key role in nociception. But recent researches have proved the increased expression of Substance P and its receptors in
Soumya Ramankutty   +5 more
doaj   +1 more source

HLA‐DR+ Schwann Cells Generate the Protumor Cancer‐Neuron‐Immune Niche in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng   +7 more
wiley   +1 more source

Clinical and pathological aspects of bovine lymphoma affecting the spinal cord

open access: yesPesquisa Veterinária Brasileira
: Clinical and pathological features of bovine lymphoma involving the spinal cord were evaluated through a retrospective study of the necropsy database from 2005 to 2017.
Lauren S. Mello   +5 more
doaj   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li   +13 more
wiley   +1 more source

Radiologic Diagnosis of Toxic Injury to Spinal Cord and Peripheral Nervous System as an Immune-Mediated Complication of Antitumor Therapy

open access: yesИнновационная медицина Кубани
Immunotherapy represents a significant breakthrough in modern oncology, being successfully used in the treatment of various malignant neoplasms including those at advanced metastatic stages.
A. E. Gerasyuta   +3 more
doaj  

Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: a pilot randomized clinical trial

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVEOxaliplatin is one of the chemotherapy regimens most used for treating colorectal cancer. One of the main limitations to its use is induction of peripheral neuropathy.
Samuel Oliveira de Afonseca   +8 more
doaj   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang   +8 more
wiley   +1 more source

BRAIN ABSCESS CAUSED BY NOCARDIA ARAOENSIS IN AN IMMUNOCOMPETENT PATIENT: CASE REPORT

open access: yesBrazilian Journal of Infectious Diseases
Brain abscess due to Nocardia is a rare central nervous system infection that primarily affects immunocompromised patients. The Nocardia asteroides complex accounts for most infections.
Isabel   +3 more
doaj   +1 more source

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