Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
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Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives. [PDF]
Dubský M +3 more
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An Exploration of Vitamin D Deficiency and Clinical Status in Friedreich's Ataxia Patients in the UK
Movement Disorders Clinical Practice, EarlyView.
Zofia Fleszar +4 more
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Risk Prediction Model for Taxane-Induced Peripheral Neuropathy in Early-Stage Cancer.
Trivedi MS +16 more
europepmc +1 more source
Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review. [PDF]
Zuo Y, Xu X, Wu C, Cui X, Li X.
europepmc +1 more source
Early and Progressive Spinal Cord Atrophy in Spinocerebellar Ataxia Type 1
Abstract Background Spinocerebellar ataxia type 1 (SCA1) is a rare, autosomal dominant neurodegenerative disorder characterized by progressive cerebellar and brainstem degeneration. Previous studies have shown that spinal cord atrophy is also a key aspect of SCA1 neuropathology.
Colette J.M. Reniers +11 more
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Pain Modulation and Central Sensitization in Painful Diabetic Peripheral Neuropathy: Updated Narrative Review and Future Directions. [PDF]
Ye D, Fairchild TJ, Vo L, Drummond PD.
europepmc +1 more source
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang +6 more
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Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting. [PDF]
Wei J +11 more
europepmc +1 more source

