Results 111 to 120 of about 1,596,501 (294)

A new type of peripheral nerve lesion

open access: yes, 1990
We report a hitherto undescribed type of peripheral nerve lesion in which pressure results in mechanical demyelinisation of a length of nerve with interruption of conduction. On release of the pressure, early recovery may follow the return of the myelin
FG St Clair Strange, R Birch
core   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

open access: yesAdvanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin   +5 more
wiley   +1 more source

Cone beam computed tomography-guided bronchoscopic sampling of peripheral pulmonary lesions: The first Indian experience

open access: yesLung India
Background: Conventional bronchoscopic approaches have a lower diagnostic yield (DY) compared to transthoracic biopsy for sampling peripheral pulmonary lesions (PPLs).
Venkata Nagarjuna Maturu   +5 more
doaj   +1 more source

Localizating and Extracting Small Peripheral Nodules of Lung with Simulating 
Radiaotherapy Combining Methylene Blue Staining

open access: yesChinese Journal of Lung Cancer, 2016
Background and objective With the extensively application of HRCT (high resolution CT) and the popularization of early lung cancer screening, the proportion of small nodullar lung cancer to be operated increases rapidly.
Feng MAO   +5 more
doaj   +1 more source

The value of navigation bronchoscopy in the diagnosis of peripheral pulmonary lesions: A meta‐analysis

open access: yes, 2020
Background To compare the diagnostic yield of peripheral pulmonary lesions (PPLs) with and without navigation system. Methods Studies dating from January 1990 to October 2019 were collected from databases.
Jiayuan Sun   +4 more
core   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

open access: yesAdvanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie   +24 more
wiley   +1 more source

Endobronchial Ultrasonography for Peripheral Pulmonary Lesions [PDF]

open access: yesUltrasound in Medicine & Biology, 2017
Noriaki Kurimoto   +3 more
openaire   +1 more source

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang   +12 more
wiley   +1 more source

A coin lesion due to pulmonary infarction : a case report [PDF]

open access: yes
A 61-year-old woman was referred for an asymptomatic coin lesion 2.0 cm in size in the periphery of the right middle lung field. Routine laboratory tests for pulmonary infections or cancer were negative.
Hara, Satoshi   +11 more
core  

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