Results 11 to 20 of about 209,971 (329)
Simultaneous inhibition of pan-phosphatidylinositol-3-kinases and MEK as a potential therapeutic strategy in peripheral T-cell lymphomas [PDF]
Haematologica, 2013 Peripheral T-cell lymphomas are very aggressive hematologic malignancies for which there is no targeted therapy. New, rational approaches are necessary to improve the very poor outcome in these patients.
Esperanza Martín-Sánchez +19 more
doaj +3 more sources
Therapeutic challenges in peripheral T-cell lymphoma [PDF]
Molecular CancerPeripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less advanced, and a significant number of patients ...
Yunpeng Luan +10 more
doaj +2 more sources
Expression of CD52 in peripheral T-cell lymphoma
Haematologica, 2007 Peripheral T-cell lymphoma unspecified (PTCL/U) is a rare tumor characterized by poor treatment response and a dismal prognosis. We studied CD52 expression in 97 PTCL/U cases by immunohistochemistry on tissue-microarrays. Furthermore, CD52 gene expression was studied in 28 cases for which RNA was available.
Pier Paolo Piccaluga +4 more
openalex +6 more sources
Controversies in the Treatment of Peripheral T‐cell Lymphoma [PDF]
HemaSphere, 2020 AbstractPeripheral T‐cell lymphomas are a heterogeneous group of rare diseases with an aggressive behavior and dismal prognosis. Their classification is complex and still evolving, and several biomolecular markers now help refine the prognosis of specific disease entities, although still have limited impact in tailoring the treatment.
Bachy, Emmanuel +8 more
openaire +7 more sources
Experimental Hematology & Oncology, 2021 Background The 2016 World Health Organization (WHO) classification introduced nodal lymphomas of T follicular helper (Tfh) cell origin, such as angioimmunoblastic T-cell lymphoma (AITL), follicular peripheral T-cell lymphoma (F-PTCL), and nodal ...
Sang Eun Yoon +6 more
doaj +1 more source
Peripheral T-cell lymphoma [PDF]
Cancer, 1989 Peripheral T-cell lymphoma is the most common type of T-cell lymphoma seen in adults in the United States. Clinical data were reviewed from 134 cases of peripheral T-cell lymphoma diagnosed in three centers. The median age of the patients was 57 years (range, 4-97 years), 59% were male, and 36 patients (27%) had a history of a preceding disorder of the
John P. Greer +10 more
openaire +3 more sources
Peripheral T-Cell Lymphomas [PDF]
Egyptian Journal of Hematology and Bone Marrow Transplantation, 2016 Nodal peripheral T cell lymphomas (TCL) are rare entities with poor prognosis including ALK+ and ALK- systemic anaplastic T-cell lymphoma (ALCL), angioimmunoblastic T cell lymphoma and peripheral T cell lymphoma – not otherwise specified. The role of PET in TCL is less well established compared to other lymphoma entities.
Maria K. Angelopoulou +2 more
openaire +3 more sources
An exploration into the origins and pathogenesis of anaplastic large cell lymphoma, anaplastic lymphoma kinase (ALK)-positive [PDF]
, 2017 T cell Non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic T cells halted in development, through to mature, circulating peripheral T cells.
Turner, SD
core +6 more sources
Morphological characterization of canine retrobulbar lymphoma [PDF]
Open Veterinary Journal, 2018 This report characterized seven cases of canine retrobulbar lymphoma that have been diagnosed during 2008 to 2014 by immunophenotyping of CD3 and Pax5. Classification of lymphoma were performed according to the revised WHO guidelines.
Natthanet Sritrakoon +4 more
doaj +1 more source
Hemato, 2022 Follicular helper T-cell (TFH) lymphomas comprise a unique group of T-cell lymphomas that represent neoplastic proliferations of follicular helper T-cells and share genetic, immunophenotypic, morphologic, and clinical features.
Karthik A. Ganapathi +2 more
doaj +1 more source