Results 191 to 200 of about 103,385 (306)

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

open access: yesJournal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source

Recurrent intussusception associated with pneumatosis cystoides coli: A pediatric case report

open access: yesJPGN Reports, EarlyView.
Abstract Pneumatosis cystoides coli (PCC) describes gas‐filled cysts within the wall of the gastrointestinal tract and is uncommon in children. We report a 7‐year‐old female with a history of recurrent ileocolic intussusception secondary to PCC. Her initial episodes of intussusception resolved spontaneously or with air enema, but no lead point was ...
Sarah Barrett   +4 more
wiley   +1 more source

Interferon‐gamma blocking as a promising treatment for severe liver dysfunction in secondary hemophagocytic lymphohistiocytosis after liver transplantation

open access: yesJPGN Reports, EarlyView.
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome that can occur after solid organ transplantation but remains underrecognized in this setting. The diagnosis is often delayed due to overlapping clinical manifestations with infection, rejection, or malignancy, and management becomes particularly ...
Chen Chen   +6 more
wiley   +1 more source

Multiparametric Ultrasound Findings of Testicular Sarcoidosis

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives To characterize the multiparametric ultrasound (MPUS) features of testicular sarcoidosis, incorporating greyscale, color Doppler ultrasound (CDUS), contrast‐enhanced ultrasound (CEUS), and strain elastography (SE), and to assess their collective diagnostic value.
Huahui Liu   +5 more
wiley   +1 more source

Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino   +3 more
wiley   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo   +5 more
wiley   +1 more source

The Global Burden of Leukemia, 1990–2021: A Systematic Analysis of Prevalence, DALYs, and Risk Factors From the Global Burden of Disease Study

open access: yesMed Research, EarlyView.
Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu   +8 more
wiley   +1 more source

Brentuximab vedotin as monotherapy or combination therapy for cutaneous peripheral T cell lymphoma – a retrospective study [PDF]

open access: hybrid
Caroline Glatzel   +6 more
openalex   +1 more source

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