Results 51 to 60 of about 558,821 (305)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Imaginea periferiei în proza lui Vasile Demetrius [PDF]

open access: yesRevista de Istorie și Teorie Literară, 2019
This paper aims to showcase one of the two ways to imagine Bucharest suburbs active in the fiction before the Great War. Based on the narrative strategies of Naturalism, V.
Alexandru Farcaș
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Centre-periphery tensions regarding Central and Eastern Europe [PDF]

open access: yes, 2012
Security issues have played an important role in widening the European Union with eight Central and Eastern European economies. The time since have proved these concerns to be correct.
Blahó, András
core   +1 more source

Peripheries - the agenda [PDF]

open access: yes, 2013
Fra første side: According to analysis for the uropean Commission, three of the four leaders in innovation in the European Union are the Nordic countries of Denmark, Finland and Sweden – Germany being the other (Innovation Union Scoreboard, http://ec.europa.eu/enterprise/policies/innovation/facts-figuresanalysis/innovation-scoreboard/index_en.htm ...
Danson, Mike, de Souza, Peter
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A core/periphery perspective on mega-event sustainability: Dystopic and utopic scenarios

open access: yes, 2021
Mega-events can captivate global audiences, stimulate economies, increase employment and endow host cities with significant tangible and intangible legacies. However, increasing problems of organisational corruption, escalating costs, exaggerated benefit
Weaver, D, McLennan, CL, Moyle, BD
core   +1 more source

The Visibility of Papers Written by Authors from European Post-Socialist Countries as an Indicator of Integration into the EU Legal System

open access: yesCroatian Yearbook of European Law and Policy, 2018
The equality of the European Union (EU) Member States is one of the principles that the European Union is based on. However, in terms of the economy, culture and influence, a hierarchy of EU Members States is evident.
Dora Zgrabljić Rotar   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

IMMANUEL WALLERSTEIN'S WORLD SYSTEM THEORY [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2010
World-systems analysis is not a theory, but an approach to social analysis and social change developed, among others by the Immanuel Wallerstein. Professor Wallerstein writes in three domains of world-systems analysis: the historical development of the ...
Cosma Sorinel
doaj  

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