Results 71 to 80 of about 582,261 (305)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Vægi atkvæða og pólitískt jafnrétti
Íslenska þjóðfélagið: The Icelandic Society, 2013 In this article an attempt is made to clarify the concept of political equality and how it relates to democratic government. The authors relate that with the general discussion on constitutional change in Iceland.
Grétar Þór Eyþórsson +1 more
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A Regional Core, Adjacent, Periphery Model for National Economic Geography Analysis [PDF]
and classifies a country’s regions into three types according to population density criteria. The regions within a country are typified as; core, adjacent, and periphery. The benefit of this classification is twofold.
Henk J.E.M. Brand
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Geo-economics and geopolitics in Europe from the aspect of a centre-periphery divide [PDF]
, 2017 The paper gives a comprehensive geo-economic analysis of Europe, providing a new, distance-based definition of core (360 km), centre (720 km), semi-periphery (1440 km) and periphery (over 1440 km), which is also relevant for other, non-European economies.
Tibor, Fehér, Fehér, Tibor
core +1 more source
Why Being a Periphery is not Honorable, and why It does not Threaten Russia
Управленческое консультирование, 2020 The foreign policy of theRussian Federationattracts the attention of experts and researchers not only during the days of obvious victories, but also during periods of serious trials.Russiamanaged not to become the periphery of any Center; this is the fi ...
N. M. Mezhevich
doaj +1 more source
Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery [PDF]
, 2014 Copyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus ...
Elizabeth Petfalski +34 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Universitas Humanística, 2008 Lately, several authors have been analyzing the changes in rural areas triggered by globalization. The concepts of new rurality and pluriactivity have allowed progress along these lines, highlighting the new difficulties facing the most vulnerable ...
Laura María Torres
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