Results 71 to 80 of about 1,006,221 (298)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The equality of the European Union (EU) Member States is one of the principles that the European Union is based on. However, in terms of the economy, culture and influence, a hierarchy of EU Members States is evident.
Dora Zgrabljić Rotar +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IMMANUEL WALLERSTEIN'S WORLD SYSTEM THEORY [PDF]
World-systems analysis is not a theory, but an approach to social analysis and social change developed, among others by the Immanuel Wallerstein. Professor Wallerstein writes in three domains of world-systems analysis: the historical development of the ...
Cosma Sorinel
doaj
Centrality metrics and localization in core-periphery networks
Two concepts of centrality have been defined in complex networks. The first considers the centrality of a node and many different metrics for it has been defined (e.g. eigenvector centrality, PageRank, non-backtracking centrality, etc).
Barucca, Paolo +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Isocrate ou l’utopie du centre
Many Greek classical authors have tried to present the fourth-century B. C. city of Athens as a capital. Isocrates, with a perseverance and a will of propaganda which made him famous among all, raises the matter of Athens’
Christian Bouchet
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Armed violence in recent years has intensified the murder of young people in the necropolitical meshes of the peripheries of Fortaleza. This article aims to map the practices of confronting armed violence developed by the Forum of Schools for Peace of ...
Laisa Forte Cavalcante +5 more
doaj
The amazing synchronicity of the Global Development (the 1300s-1450s). An institutional approach to the globalization of the late Middle Ages [PDF]
In a new approach to a long-ranging debate on the causes of the Late Medieval Debasement, we offer an institutional case-study of Russia and the Levant.
Badalian, Lucy, Krivorotov, Victor
core

