Results 61 to 70 of about 416,455 (267)
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Universitas Humanística, 2008 Lately, several authors have been analyzing the changes in rural areas triggered by globalization. The concepts of new rurality and pluriactivity have allowed progress along these lines, highlighting the new difficulties facing the most vulnerable ...
Laura María Torres
doaj
FIELD ORGANIZATION OF CONCERTS “WAR” AND “PEACE” IN THE MODERN LINGUISTIC WORLD VIEW
RUDN Journal of Language Studies, Semiotics and Semantics, 2019 Nowadays anthropocentric approach is widely used in the study of national culture in the Russian and foreign linguistics. It proves the emergence of linguistic and cultural trends in modern science, in which there is an interest in the issues of ...
Elena A Golubenko
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Peripheries - the agenda [PDF]
, 2013 Fra første side: According to analysis for the uropean Commission, three of the four leaders in innovation in the European Union are the Nordic countries of Denmark, Finland and Sweden – Germany being the other (Innovation Union Scoreboard, http://ec.europa.eu/enterprise/policies/innovation/facts-figuresanalysis/innovation-scoreboard/index_en.htm ...
Danson, Mike, de Souza, Peter
openaire +2 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
TIPOLOGIZATION OF TERRITORIES OF REGIONS ON THE ECONOMIC POTENTIAL OF ECONOMIC WAYS [PDF]
Krymskij Naučnyj Vestnik, 2015 The article analyze and application tools of region rating level of potential and way economy on case of agricultural complex from a position of achievement of the balanced development of regional economy on model of import substitution.
Tatiana Kushnarenko
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Socio-economic changes in the borderlands of the Visegrad Group (V4) countries
Moravian Geographical Reports, 2015 Under the influence of globalization and state integration processes, the importance of a border as a barrier is gradually decreasing. Borderlands are still perceived as specific phenomena, however, not only in terms of historical development but ...
Máliková Lucia +3 more
doaj +1 more source