Results 61 to 70 of about 582,261 (305)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
TIPOLOGIZATION OF TERRITORIES OF REGIONS ON THE ECONOMIC POTENTIAL OF ECONOMIC WAYS [PDF]
Krymskij Naučnyj Vestnik, 2015 The article analyze and application tools of region rating level of potential and way economy on case of agricultural complex from a position of achievement of the balanced development of regional economy on model of import substitution.
Tatiana Kushnarenko
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Ni original ni copia: versiones musicales entre el mainstream y la periferia
Resonancias, 2017 In this article, we analyze peripheral musical versions that perform translations from songs of the international mainstream Pop and Rock to Brazilian musical genres like Electronic Forró, Tecnobrega and Sertanejo .
Jeder Silveira Janotti Junior +1 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Centre-periphery tensions regarding Central and Eastern Europe [PDF]
, 2012 Security issues have played an important role in widening the European Union with eight Central and Eastern European economies. The time since have proved these concerns to be correct.
Blahó, András
core +1 more source
Eastern Europe. On the centenary of the political project [PDF]
Baltic Region, 2016 This article describes the characteristics of Eastern Europe as a political pro-ject. The author considers the genesis of Eastern Europe as a political region and identifies several periods in its history.
Mezhevich Nikolai
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Abnormal center-periphery gradient in spatial attention in simultanagnosia [PDF]
, 2014 This work was supported by the Danish Medical Research Councils [grant number 09-072209 to DB] .Patients suffering from simultanagnosia cannot perceive more than one object at a time. The underlying mechanism is incompletely understood. One hypothesis is
Balslev, Daniela +4 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source