Results 61 to 70 of about 353,669 (203)

Age-At-Injury Influences the Glial Response to Traumatic Brain Injury in the Cortex of Male Juvenile Rats

Frontiers in Neurology, 2022
Few translational studies have examined how age-at-injury affects the glial response to traumatic brain injury (TBI). We hypothesized that rats injured at post-natal day (PND) 17 would exhibit a greater glial response, that would persist into early ...
Tabitha R. F. Green, Sean M. Murphy, J. Bryce Ortiz, J. Bryce Ortiz, Rachel K. Rowe, Rachel K. Rowe, Rachel K. Rowe   +6 more
doaj   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Convergent Projections from Perirhinal and Postrhinal Cortices Suggest a Multisensory Nature of Lateral, but Not Medial, Entorhinal Cortex

Cell Reports, 2019
Summary: The current model of the organization of the medial temporal lobe (MTL) episodic memory system assumes that two functionally different “where” and “what” pathways enter MTL as parallel parahippocampal cortex (PHC)-medial entorhinal cortex (MEC ...
Thanh P. Doan, Maria J. Lagartos-Donate, Eirik S. Nilssen, Shinya Ohara, Menno P. Witter   +4 more
doaj   +1 more source

The spatial learning task of Lhermitte and Signoret: Marker of bilateral hippocampal dysfunction in temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Bilateral hippocampal compromise in temporal lobe epilepsy (TLE) substantially increases the risk of significant adverse memory outcomes following unilateral anterior temporal lobectomy and may contraindicate surgery. The Spatial Learning Task (SLT) of Lhermitte and Signoret (1972) is a simple object–location arbitrary associative ...
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +6 more
wiley   +1 more source

Cytoarchitecture of the canine perirhinal and postrhinal cortex

Acta Neurobiologiae Experimentalis, 2003
The perirhinal cortex in the dog's brain is composed of two traditional Brodmann's areas: 35 and 36. Area 35 is situated along the entire rostro-caudal extent of the fundus of the posterior rhinal sulcus, whereas area 36 occupies its lateral bank. In this study, four subdivisions were distinguished in area 35 based on cytoarchitectonic differentiation.
Agnieszka, Woźnicka, Anna, Kosmal
openaire   +2 more sources

The role of the perirhinal cortex in visual learning in the rat [PDF]

, 1999
The aim of this thesis was to investigate the role of the perirhinal cortex in visual discrimination learning in the rat. Experiment one measured postoperative reacquisition of two sets of concurrent visual discriminations acquired at different time ...
Machin, Penelope Elizabeth
core  

The topology of connections between rat prefrontal and temporal cortices

Frontiers in Systems Neuroscience, 2015
Understanding the structural organisation of the prefrontal cortex (PFC) is an important step towards determining its functional organisation. Here we investigated the organisation of PFC using different neuronal tracers.
Stacey eBedwell, E Ellen eBillett, Jonathan eCrofts, Danielle M MacDonald, Chris John Tinsley   +4 more
doaj   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

Interdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang, Baoyuan Zhu, Yuanyuan Huang, Liqin Liang, Zhaobo Li, Yunheng Diao, Minxin Guo, Heng Zhang, Jing Zhou, Fengchun Wu, Kai Wu   +10 more
wiley   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Evaluating the Cognitive Impacts of Drospirenone, a Spironolactone-Derived Progestin, Independently and in Combination With Ethinyl Estradiol in Ovariectomized Adult Rats

Frontiers in Neuroscience, 2022
Oral contraceptives and hormone therapies require a progestogen component to prevent ovulation, curtail uterine hyperplasia, and reduce gynecological cancer risk.
Stephanie V. Koebele, Stephanie V. Koebele, Mallori L. Poisson, Mallori L. Poisson, Justin M. Palmer, Justin M. Palmer, Claire Berns-Leone, Claire Berns-Leone, Steven N. Northup-Smith, Steven N. Northup-Smith, Veronica L. Peña, Veronica L. Peña, Isabel M. Strouse, Isabel M. Strouse, Haidyn L. Bulen, Haidyn L. Bulen, Shruti Patel, Shruti Patel, Corissa Croft, Corissa Croft, Heather A. Bimonte-Nelson, Heather A. Bimonte-Nelson   +21 more
doaj   +1 more source