Results 51 to 60 of about 17,014 (179)
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle +4 more
wiley +1 more source
Accelerated forgetting of contextual details due to focal medio-dorsal thalamic lesion [PDF]
Effects of thalamic nuclei damage and related white matter tracts on memory performance are still debated. This is particularly evident for the medio-dorsal thalamus which has been less clear in predicting amnesia than anterior thalamus changes.
Laurie eMiller +8 more
core +2 more sources
Reduced CB1 Cannabinoid Receptor Expression in Alzheimer's Disease and Transgenic Mouse Models
CB1 receptor (CB1R) expression was significantly reduced in the hippocampus, medial frontal gyrus, and superior temporal gyrus of Alzheimer's patients. CB1R levels negatively correlated with amyloid‐β and tau pathology. In addition, CB1R expression was also reduced in the cortex of 5xFAD mice and in the hippocampus of Tg4‐42 mice.
Nike von Borcke +4 more
wiley +1 more source
Altered Brain Structure in an ATRX‐Deficient Mouse Model of Autism Spectrum Disorder
ABSTRACT Mutations in the ATRX gene are a primary cause of alpha‐thalassemia intellectual disability X‐linked (ATRX) syndrome, which is characterized by intellectual disability, autism, and a range of brain structural abnormalities, including microcephaly.
Katherine Quesnel +3 more
wiley +1 more source
The Hippocampus is Preferentially Associated with Memory for Spatial Context [PDF]
The existence of a functional-anatomic dissociation for retrieving item versus contextual information within subregions of the medial temporal lobe (MTL) is currently under debate.
Ross, Robert S., Slotnick, Scott D.
core +2 more sources
The Role of Dopamine Signaling and Neuroinflammation in Age‐Related Cognitive Dysfunction
We reveal early disruption in synaptic integrity (PSD‐95, synaptophysin, BDNF), increased dopamine clearance (Comt, Net), and inflammatory signaling (Nfkb, Socs3) in the PFC, while the hippocampus remains largely resistant. These molecular “warning signs” precede behavioral deficits, highlighting potential targets for early intervention to protect ...
Junior Bowen +4 more
wiley +1 more source
Nps‐Expressing Neurons Receive Extensive Input From Auditory Brainstem Nuclei
Nps‐expressing neurons receive input from auditory brainstem nuclei, with additional afferents from the reticular formation, midbrain, hypothalamus, and extended amygdala. While rabies retrograde labeling in the cerebral cortex was sparse, cholera toxin beta (CTb) revealed copious input, and anterograde tracing identified many axons and boutons ...
Richie Zhang +2 more
wiley +1 more source
Medial perirhinal cortex disambiguates confusable objects [PDF]
Our brain disambiguates the objects in our cluttered visual world seemingly effortlessly, enabling us to understand their significance and to act appropriately.
Kivisaari, Sasa L. +3 more
core
EMDR therapy for PTSD after motor vehicle accidents: meta-analytic evidence for specific treatment [PDF]
Motor vehicle accident (MVA) victims may suffer both acute and post-traumatic stress disorders (PTSD). With PTSD affecting social, interpersonal and occupational functioning, clinicians as well as the National Institute of Health are very interested in ...
Boccia, Maddalena +4 more
core +1 more source
The gross anatomy of the sound localization circuit in the chicken brainstem was quantified with 3D reconstructions from serial sections and measurements of the interconnecting pathways. A rostral‐to‐caudal length gradient was measured in both the crossed dorsal cochlear track and the ipsilateral loop.
David M. Harris
wiley +1 more source

