A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat. [PDF]
PLoS ONE, 2012 BACKGROUND: We aimed to further understand the relationship between cAMP concentration and mnesic performance. METHODS AND FINDINGS: Rats were injected with milrinone (PDE3 inhibitor, 0.3 mg/kg, i.p.), rolipram (PDE4 inhibitor, 0.3 mg/kg, i.p.) and/or ...
Maïte Hotte +4 more
doaj +1 more source
Perceptual functions of perirhinal cortex in rats: zero-delay object recognition and simultaneous oddity discriminations [PDF]
, 2007 The perirhinal cortex (PRh) is widely accepted as having an important role in object recognition memory in humans and animals. Contrary to claims that PRh mediates declarative memory exclusively, previous evidence suggests that PRh has a role in the ...
Bussey, Timothy J. +4 more
core +1 more source
Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]
, 2011 The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Brown, MW +27 more
core +1 more source
Perhirhinal cortex resolves feature ambiguity in configural object recognition and perceptual oddity tasks [PDF]
, 2007 The perirhinal cortex (PRh) has a well-established role in object recognition memory. More recent studies suggest that PRh is also important for two-choice visual discrimination tasks.
Rosemary A. Cowell +9 more
core +1 more source
Developmental Cognitive Neuroscience, 2015 To investigate the role of the perirhinal cortex on the development of recognition measured by the visual paired-comparison (VPC) task, infant monkeys with neonatal perirhinal lesions and sham-operated controls were tested at 1.5, 6, 18, and 48 months of
Alyson Zeamer +3 more
doaj +1 more source
NMDA receptor plasticity in the perirhinal and prefrontal cortices is crucial for the acquisition of long-term object-in-place associative memory [PDF]
, 2008 A key process for recognition memory is the formation of associations between an object and the place in which it was encountered, a process that has been shown to require the perirhinal (PRH) and medial prefrontal (mPFC) cortices.
Barker, Gareth, Warburton, E Clea
core +1 more source
Frontiers in Human Neuroscience, 2014 Recent research suggests that the medial temporal lobe (MTL) is involved in perception as well as in declarative memory. Amnesic patients with focal MTL lesions and semantic dementia patients showed perceptual deficits when discriminating faces and ...
Victoria Chantal McLelland +5 more
doaj +1 more source
Critical role of the cholinergic system for object-in-place associative recognition memory [PDF]
, 2009 Object-in-place memory, which relies on the formation of associations between an object and the place in which it was encountered, depends upon a neural circuit comprising the perirhinal (PRH) and medial prefrontal (mPFC) cortices.
Warburton, Elizabeth C, Barker, GRI
core +1 more source
Lateral entorhinal cortex is necessary for associative but not nonassociative recognition memory [PDF]
, 2013 This work was supported by BBSRC [Grant number BB/I019367/1]The lateral entorhinal cortex (LEC) provides one of the two major input pathways to the hippocampus and has been suggested to process the nonspatial contextual details of episodic memory ...
Milner, Helen Louise +3 more
core +1 more source
Frontiers in Systems Neuroscience, 2016 The lateral prefrontal cortex is known for its contribution to working memory (WM) processes in both humans and animals. Yet, recent studies indicate that the prefrontal cortex is part of a broader network of interconnected brain areas involved in WM ...
Alison R Weiss +3 more
doaj +1 more source