Disambiguation of visual stimuli correlates with activity in bilateral medial temporal lobe structures [PDF]
We are organisms adapted to recognize patterns around us in order to avoid ambiguity and indecision and there are inter-individual differences at this level.
Dragos Cirneci +4 more
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Selective perceptual impairments after perirhinal cortex ablation. [PDF]
It has been suggested that the primate perirhinal cortex contributes exclusively to memory. However, recent studies in macaque monkeys have implied that the perirhinal cortex may also contribute to object perception. To investigate whether the perirhinal
Michael C. A. Booth +9 more
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Why is there a special issue on perirhinal cortex in a journal called hippocampus? The perirhinal cortex in historical perspective [PDF]
AbstractDespite its small size, the perirhinal cortex (PRh) plays a central role in understanding the cerebral cortex, vision, and memory; it figures in discussions of cognitive capacities as diverse as object perception, semantic knowledge, feelings of familiarity, and conscious recollection. Two conceptual constructs have encompassed PRh. The current
Elisabeth A, Murray, Steven P, Wise
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Prefrontal Pathways Provide Top-Down Control of Memory for Sequences of Events
Summary: We remember our lives as sequences of events, but it is unclear how these memories are controlled during retrieval. In rats, the medial prefrontal cortex (mPFC) is positioned to influence sequence memory through extensive top-down inputs to ...
Maanasa Jayachandran +5 more
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Limbic and olfactory cortical circuits in focal seizures
Epilepsies affecting the limbic regions are common and generate seizures often resistant to pharmacological treatment. Clinical evidence demonstrates that diverse regions of the mesial portion of the temporal lobe participate in limbic seizures; these ...
Marco de Curtis +2 more
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Perirhinal cortex ablation impairs visual object identification. [PDF]
Impairments in both recognition memory and concurrent discrimination learning have been shown to follow perirhinal cortex ablation in the monkey. The pattern of these impairments is consistent with the hypothesis that the perirhinal cortex has a role in ...
Buckley, MJ +5 more
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Analyses of complex behaviors across the lifespan of animals can reveal the brain regions that are impacted by the normal aging process, thereby, elucidating potential therapeutic targets.
Carol A Barnes, Sara N Burke, L. eRyan
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Multisynaptic inputs from the medial temporal lobe to V4 in macaques. [PDF]
Retrograde transsynaptic transport of rabies virus was employed to undertake the top-down projections from the medial temporal lobe (MTL) to visual area V4 of the occipitotemporal visual pathway in Japanese monkeys (Macaca fuscata). On day 3 after rabies
Taihei Ninomiya +3 more
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The Perirhinal Cortex and Long-Term Familiarity Memory [PDF]
To analyse the functions of the perirhinal cortex, the activity of single neurons in the perirhinal cortex was recorded while macaques performed a delayed matching-to-sample task with up to three intervening stimuli. Some neurons had activity related to working memory, in that they responded more to the sample than to the match image within a trial, as
Rolls, E, Franco, L, Stringer, S
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Perirhinal Cortex Neuronal Activity is Actively Related to Working Memory in the Macaque
Lesion studies suggest that the perirhinai cortex plays a role in object recognition memory. To analyze its role, we recorded the activity of single neurons in the perirhinal cortex in a rhesus monkey (Macaca mulatta) performing a delayed matching-to ...
Christian Hölscher, Edmund T. Rolls
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