Results 21 to 30 of about 8,228 (169)

A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: We aimed to further understand the relationship between cAMP concentration and mnesic performance. METHODS AND FINDINGS: Rats were injected with milrinone (PDE3 inhibitor, 0.3 mg/kg, i.p.), rolipram (PDE4 inhibitor, 0.3 mg/kg, i.p.) and/or ...
Maïte Hotte   +4 more
doaj   +1 more source

Medial temporal pathways for contextual learning: Network c- mapping in rats with or without perirhinal cortex lesions

open access: yesBrain and Neuroscience Advances, 2017
Background: In the rat brain, context information is thought to engage network interactions between the postrhinal cortex, medial entorhinal cortex, and the hippocampus.
Lisa Kinnavane   +3 more
doaj   +1 more source

Perirhinal cortex learns a predictive map of the task environment. [PDF]

open access: yesNat Commun, 2023
ABSTRACT Goal-directed tasks involve acquiring an internal model, known as a predictive map, of relevant stimuli and associated outcomes to guide behavior. Here, we identified neural signatures of a predictive map of task behavior in perirhinal cortex (Prh). Mice learned to perform a tactile working memory task by classifying sequential
Lee DG   +9 more
europepmc   +4 more sources

The development of object recognition memory in rhesus macaques with neonatal lesions of the perirhinal cortex

open access: yesDevelopmental Cognitive Neuroscience, 2015
To investigate the role of the perirhinal cortex on the development of recognition measured by the visual paired-comparison (VPC) task, infant monkeys with neonatal perirhinal lesions and sham-operated controls were tested at 1.5, 6, 18, and 48 months of
Alyson Zeamer   +3 more
doaj   +1 more source

Model of Familiarity Discrimination in the Perirhinal Cortex

open access: yesJournal of Computational Neuroscience, 2001
Much evidence indicates that recognition memory involves two separable processes, recollection and familiarity discrimination, with familiarity discrimination being dependent on the perirhinal cortex of the temporal lobe. Here, we describe a new neural network model designed to mimic the response patterns of perirhinal neurons that signal information ...
Rafal Bogacz   +2 more
openaire   +3 more sources

Stimulus familiarity modulates functional connectivity of the perirhinal cortex and anterior hippocampus during visual discrimination of faces and objects

open access: yesFrontiers in Human Neuroscience, 2014
Recent research suggests that the medial temporal lobe (MTL) is involved in perception as well as in declarative memory. Amnesic patients with focal MTL lesions and semantic dementia patients showed perceptual deficits when discriminating faces and ...
Victoria Chantal McLelland   +5 more
doaj   +1 more source

Integrating Visual and Tactile Information in the Perirhinal Cortex [PDF]

open access: yesCerebral Cortex, 2009
By virtue of its widespread afferent projections, perirhinal cortex is thought to bind polymodal information into abstract object-level representations. Consistent with this proposal, deficits in cross-modal integration have been reported after perirhinal lesions in nonhuman primates.
Holdstock, J   +4 more
openaire   +6 more sources

Homosexual women have less grey matter in perirhinal cortex than heterosexual women.

open access: yesPLoS ONE, 2007
Is sexual orientation associated with structural differences in the brain? To address this question, 80 homosexual and heterosexual men and women (16 homosexual men and 15 homosexual women) underwent structural MRI.
Jorge Ponseti   +7 more
doaj   +1 more source

Neonatal perirhinal lesions in rhesus macaques alter performance on working memory tasks with high proactive interference

open access: yesFrontiers in Systems Neuroscience, 2016
The lateral prefrontal cortex is known for its contribution to working memory (WM) processes in both humans and animals. Yet, recent studies indicate that the prefrontal cortex is part of a broader network of interconnected brain areas involved in WM ...
Alison R Weiss   +3 more
doaj   +1 more source

Disambiguation of visual stimuli correlates with activity in bilateral medial temporal lobe structures [PDF]

open access: yesRomanian Journal of Neurology, 2013
We are organisms adapted to recognize patterns around us in order to avoid ambiguity and indecision and there are inter-individual differences at this level.
Dragos Cirneci   +4 more
doaj   +1 more source

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