Perirhinal cortex and the recognition of relative familiarity [PDF]
Spontaneous object recognition (SOR) is a widely used task of recognition memory in rodents which relies on their propensity to explore novel (or relatively novel) objects. Network models typically define perirhinal cortex as a region required for recognition of previously seen objects largely based on findings that lesions or inactivations of this ...
Ameen-Ali, Kamar E. +5 more
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Propagation of Neocortical Inputs in the Perirhinal Cortex [PDF]
The perirhinal area is a rostrocaudally oriented strip of cortex in which lesions produce memory and perceptual impairments. It receives topographically organized transverse projections from associative neocortical areas and is endowed with intrinsic longitudinal connections that could distribute neocortical inputs in the rostrocaudal axis.
M, Martina, S, Royer, D, Paré
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Perirhinal cortex and feature-ambiguous discriminations [PDF]
Perirhinal cortex is often regarded as part of a medial temporal lobe (MTL) memory system, mediating memory selectively, and having little role in other functions such as perception (e.g., Squire and Zola-Morgan 1991; Buffalo et al. 1998, 1999; Squire et al. 2004).
Timothy J, Bussey +2 more
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The Perirhinal Cortex and Recognition Memory Interference [PDF]
There has recently been an increase in interest in the effects of visual interference on memory processing, with the aim of elucidating the role of the perirhinal cortex (PRC) in recognition memory. One view argues that the PRC processes highly complex conjunctions of object features, and recent evidence from rodents suggests that these representations
Hilary C, Watson, Andy C H, Lee
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Perirhinal cortex learns a predictive map of the task environment. [PDF]
ABSTRACT Goal-directed tasks involve acquiring an internal model, known as a predictive map, of relevant stimuli and associated outcomes to guide behavior. Here, we identified neural signatures of a predictive map of task behavior in perirhinal cortex (Prh). Mice learned to perform a tactile working memory task by classifying sequential
Lee DG +9 more
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Perirhinal cortex and temporal lobe epilepsy [PDF]
The perirhinal cortex-which is interconnected with several limbic structures and is intimately involved in learning and memory-plays major roles in pathological processes such as the kindling phenomenon of epileptogenesis and the spread of limbic seizures.
Giuseppe eBiagini +6 more
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Model of Familiarity Discrimination in the Perirhinal Cortex
Much evidence indicates that recognition memory involves two separable processes, recollection and familiarity discrimination, with familiarity discrimination being dependent on the perirhinal cortex of the temporal lobe. Here, we describe a new neural network model designed to mimic the response patterns of perirhinal neurons that signal information ...
Rafal Bogacz +2 more
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Parallel and convergent processing in grid cell, head-direction cell, boundary cell, and place cell networks. [PDF]
The brain is able to construct internal representations that correspond to external spatial coordinates. Such brain maps of the external spatial topography may support a number of cognitive functions, including navigation and memory.
Brandon, Mark P +2 more
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Integrating Visual and Tactile Information in the Perirhinal Cortex [PDF]
By virtue of its widespread afferent projections, perirhinal cortex is thought to bind polymodal information into abstract object-level representations. Consistent with this proposal, deficits in cross-modal integration have been reported after perirhinal lesions in nonhuman primates.
Holdstock, J +4 more
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Finding and not finding rat perirhinal neuronal responses to novelty:Rat perirhinal neuronal responses to novelty [PDF]
There is much evidence that the perirhinal cortex of both rats and monkeys is important for judging the relative familiarity of visual stimuli. In monkeys many studies have found that a proportion of perirhinal neurons respond more to novel than familiar
Aggleton +59 more
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