Results 81 to 90 of about 17,084 (218)

Recognition Memory Dysfunction Relates to Hippocampal Subfield Volume: A Study of Cognitively Normal and Mildly Impaired Older Adults. [PDF]

open access: yes, 2018
ObjectivesThe current study examined recognition memory dysfunction and its neuroanatomical substrates in cognitively normal older adults and those diagnosed with mild cognitive impairment (MCI).MethodsParticipants completed the Mnemonic Similarity Task,
Bennett, Ilana J   +2 more
core   +2 more sources

APOE‐mediated sex differences in microvascular pathology and AD‐associated proteinopathies in the medial temporal lobe

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Cerebral small vessel disease (CSVD) contributes to the development of Alzheimer's disease (AD) dementia and co‐occurs with AD‐associated proteinopathies. However, how sex modulates the interaction between CSVD and AD‐associated proteinopathies in the medial temporal lobe (MTL) remains unclear.
Francesco Bax   +14 more
wiley   +1 more source

Dual functions of perirhinal cortex in fear conditioning [PDF]

open access: yesHippocampus, 2012
AbstractThe present review examines the role of perirhinal cortex (PRC) in Pavlovian fear conditioning. The focus is on rats, partly because so much is known, behaviorally and neurobiologically, about fear conditioning in these animals. In addition, the neuroanatomy and neurophysiology of rat PRC have been described in considerable detail at the ...
Brianne A, Kent, Thomas H, Brown
openaire   +2 more sources

Altered locus coeruleus links to atrophy and hypometabolism in individuals with high Alzheimer's disease biomarkers

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The locus coeruleus (LC), the first region to contain tau pathology in Alzheimer's disease (AD), releases norepinephrine, which has a neuroprotective role. We examined whether LC integrity relates to whole‐brain integrity and how AD biomarkers may moderate this relationship.
Emilie Foyard   +9 more
wiley   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae   +53 more
wiley   +1 more source

Differential cortical c-Fos and Zif-268 expression after object and spatial memory processing in a standard or episodic-like object recognition task

open access: yesFrontiers in Behavioral Neuroscience, 2013
Episodic memory reflects the capacity to recollect what, where and when a specific event happened in an integrative manner. Animal studies have suggested that the medial temporal lobe and the medial pre-frontal cortex are important for episodic-like ...
Flávio F Barbosa   +7 more
doaj   +1 more source

Preponderance of Late-spiking Neurons in Rat Lateral Amygdala [PDF]

open access: yes, 2003
Whole-cell recordings from rat lateral amygdala (LA) revealed two populations of principal neurons, that have similar pyramid-like morphologies but differing in firing pattern: late-spiking (LS, 66%) and regular-spiking (RS, 34%).
Brown, Dr Thomas H., McNay, Dr Ewan C.
core  

International Veterinary Epilepsy Task Force recommendations for systematic sampling and processing of brains from epileptic dogs and cats [PDF]

open access: yes, 2015
Traditionally, histological investigations of the epileptic brain are required to identify epileptogenic brain lesions, to evaluate the impact of seizure activity, to search for mechanisms of drug-resistance and to look for comorbidities.
A Jeans   +75 more
core   +7 more sources

Identifying neuropathologic disease in primary progressive aphasia using narrative speech

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION We present an application of artificial intelligence to narrative speech with the primary objective of predicting neuropathologic disease underlying primary progressive aphasia (PPA). METHODS Using natural language processing toolkits, features were extracted from transcribed narratives of the Cinderella story.
Daniel B. Gutstein   +12 more
wiley   +1 more source

Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study

open access: yesActa Neuropathologica Communications, 2019
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative condition associated with repetitive traumatic brain injury (rTBI) seen in contact-sport athletes and military personnel.
Christy M. Kelley   +2 more
doaj   +1 more source

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