Results 31 to 40 of about 41,745 (203)

Mechanisms of Peritoneal Mesothelial Cells in Peritoneal Adhesion

open access: yesBiomolecules, 2022
A peritoneal adhesion (PA) is a fibrotic tissue connecting the abdominal or visceral organs to the peritoneum. The formation of PAs can induce a variety of clinical diseases. However, there is currently no effective strategy for the prevention and treatment of PAs.
Ruipeng Wang, Tiankang Guo, Junliang Li
openaire   +3 more sources

The role of polymeric synthetic materials in the development of postoperative adhesion of the peritoneum(experimental study)

open access: yesActa Biomedica Scientifica, 2018
Background. Animal models for adhesions induction are heterogeneous and often poorly described. The objective of this study was to determine the impact of surgical trauma with the use of meshes and sutures on postoperative peritoneal adhesions.
I. Y. Bondarevskiy   +2 more
doaj   +1 more source

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer [PDF]

open access: yes, 2019
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics ...
Ceelen, Wim   +7 more
core   +2 more sources

Peritoneal adhesion index (PAI): proposal of a score for the “ignored iceberg” of medicine and surgery

open access: yesWorld Journal of Emergency Surgery, 2013
Peritoneal adhesions describe a condition in which pathological bonds form between the omentum, the small and large bowels, the abdominal wall, and other intra-abdominal organs. Different classification systems have been proposed, but they do not resolve
Coccolini Federico   +12 more
doaj   +1 more source

Laparoscopic peritoneal lavage. Our experience and review of the literature [PDF]

open access: yes, 2016
NTRODUCTION: Over the years various therapeutic techniques for diverticulitis have been developed. Laparoscopic peritoneal lavage (LPL) appears to be a safe and useful treatment, and it could be an effective alternative to colonic resection in emergency
Desiderio, Jacopo   +8 more
core   +4 more sources

Modified Adenovirus Reduces De Novo Peritoneal Adhesions in Rats and Limits Off-Target Transfection. Role of EZH2 in Adhesion Formation

open access: yesJournal of Investigative Surgery, 2017
Aim of the study: Adenovector encoding tissue plasminogen activator (tPA) was shown to reduce experimental peritoneal adhesion. We investigated the targeting potential of our modified adenovector, its ability to reduce adhesions and the epigenetic role ...
Hussein M. Atta   +7 more
doaj   +1 more source

Intestinal Obstruction Secondary to Postoperative Peritoneal Adhesions: the Tolerability of the Conservative Treatment [PDF]

open access: yesModern Medicine, 2018
Introduction: The present study aims to determine the mean duration of the conservative management that can be tolerated by the patients with intestinal obstruction secondary to the postoperative peritoneal adhesions, in order to postpone the surgical ...
Simona Bobic   +3 more
doaj   +1 more source

Targeting the tumor microenvironment in colorectal peritoneal metastases

open access: yes, 2020
Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC) patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the efficacy of current treatment modalities, including surgery and intraperitoneal (
Ceelen, Wim   +4 more
core   +1 more source

Biologically Targeted Photo‐Crosslinkable Nanopatch to Prevent Postsurgical Peritoneal Adhesion

open access: yesAdvanced Science, 2019
Peritoneal adhesion occurs in a majority of patients following abdominal surgery and can result in significant side effects and complications. Current strategies to minimize adhesions involve the use of nontargeted anatomical barriers that are either ...
Yu Mi   +9 more
doaj   +1 more source

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